AIDS and the Nervous System


Infection with Human immunodeficiency virus (HIV) is associated with a number of neurological disorders. These disorders arise either as a result of systemic immunosuppression or due to infection with HIV itself.

Keywords: HIV; dementia; myelopathy; peripheral neuropathy; neurological diseases

Figure 1.

Neurological disorders related to the course of human immunodeficiency virus infection and the degree of systemic immunosuppression. CD, cluster of differentiation; CNS, central nervous system; PNS, peripheral nervous system; AIDS, acquired immune deficiency syndrome; ARC, AIDS‐related complex. From Glass and Johnson (1996) with permission, from the Annual Review of Neuroscience, Volume 19, © 1996, Annual Reviews.


Further Reading

Epstein LG and Gendelman HE (1993) Human immunodeficiency virus type 1 infection of the nervous system: pathogenetic mechanisms. Annals of Neurology 33: 429–436.

Glass JD and Johnson RT (1996) AIDS and the nervous system. Annual Review of Neuroscience 19: 1–26.

Levy JA (1998) HIV and the Pathogenesis of AIDS, 2nd edn. Washington, DC: ASM Press.

McArthur JC (1987) Neurological manifestations of AIDS. Medicine 66: 407–437.

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How to Cite close
Glass, Jonathan D, and Wesselingh, Steven L(Jan 2003) AIDS and the Nervous System. In: eLS. John Wiley & Sons Ltd, Chichester. [doi: 10.1038/npg.els.0000006]