Synaptic Plasticity: Short Term


The strength of synaptic transmission can increase or decrease during repetitive presynaptic activity. These changes, usually due to variations in the amount of transmitter released by each action potential, dynamically shape the information transfer characteristics of synapses.

Keywords: facilitation; posttetanic potentiation; depression; calcium; transmitter release

Figure 1.

The different kinetic components of short‐term synaptic plasticity.



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Further Reading

Fisher SA, Fischer TM and Carew TJ (1997) Multiple overlapping processes underlying short‐term synaptic enhancement. Trends in Neurosciences 20: 170–177.

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Zucker RS and Regehr WG (2002) Short‐term synaptic plasticity. Annual Review of Physiology 64: 355–406.

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Zucker, Robert S(Sep 2005) Synaptic Plasticity: Short Term. In: eLS. John Wiley & Sons Ltd, Chichester. [doi: 10.1038/npg.els.0004054]