Biological Control by Microorganisms

Biological control is the use of natural enemies to reduce the numbers of a pest organism. Such natural enemies include pathogenic microorganisms. Biological control agents can be both less toxic and more flexible than chemical pesticides, although their high specificity can impose limitations on commercial development.

Keywords: biological control; biocontrol; microorganisms; Bacillus thuringiensis; baculovirus; bacteriophage

Figure 1. Insecticidal effect of Bacillus thuringiensis (Bt). These effects are produced by a complex of crystalline toxins. Eaten by the insect larvae these damage the gut, allowing a lethal generalized infection. The infection generally does not spread to new hosts.
Figure 2. Baculovirus structure. Baculoviruses all form protective ‘occlusion bodies’ around the infectious nucleocapsids, and are divided into two genera. These are the Nucleopolyhedroviruses, in which a single occlusion body (OB) contains multiple infectious units and the Granuloviruses, in which each OB contains a single infectious unit. During infection of the host, a nonoccluded or ‘budded’ form of the virus is produced which lacks the occlusion body. The agents formerly classified as ‘nonoccluding baculoviruses’, including Oryctes rhinoceros virus, are now considered to belong to an unclassified group of baculovirus-like agents.
Figure 3. Insecticidal effect of generalized baculovirus infection. Baculoviruses within occlusion bodies are eaten by insect larvae. The occlusion body dissolves in the insect gut releasing viruses that infect the cells of the gut by growing there. The virus then spreads throughout the body of the insect, killing it and releasing large amounts of virus from the liquefied mass that results.
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 References
    Blum B (2002) Blocked opportunities for bio-control. Pesticides News 57: 18. http://www.pan-uk.org/pestnews/pn57/pn57p18.html.
    Crickmore N, Zeigler DR, Feitelson J et al. (1998) Revision of the nomenclature for the Bacillus thuringiensis pesticidal crystal proteins. Microbiology and Molecular Biology Reviews 62: 807–813.
    book Crickmore N, Zeigler DR, Schnepf E et al. (2005) Bacillus thuringiensis Toxin Nomenclature University of Sussex. http://www.biols.susx.ac.uk/home/Neil_Crickmore/Bt/intro.html.
    other Environmental Protection Agency (EPA) (2004) Biopesticides. http://www.epa.gov/pesticides/biopesticides/.
    Fedorak RN and Madsen KL (2004) Probiotics and prebiotics in gastrointestinal disorders. Current Opinions in Gastroenterology 20: 146–155.
    other Guillon M (2004) Current World Situation on Acceptance and Marketing of Biological Control Agents (BCAs). International Biocontrol Manufacturers Association position paper. http://www.ibma.ch/pdf/20041028%20Presentation%20BCAs%20Thailand%20%20&%20Indonesia%20Cuba.pdf.
    book Harper DR (1998) Molecular Virology. Oxford, UK: Bios Scientific Publishers.
    book Hunter-Fujita FR, Entwistle PF, Evans HF and Crooke NE (1998) Insect Viruses and Pest Management. Chichester, UK: Wiley.
    other ProMED (2000) ProMed-mail. International Society for Infectious Diseases. http://www.promedmail.org/.
    Soothill J, Hawkins C, Harper D and Anggard E (2004) Therapeutic use of bacteriophages. Lancet Infectious Diseases 4: 544–545.
    Stewart LM, Hirst M, Lopez Ferber M et al. (1991) Construction of an improved baculovirus insecticide containing an insect-specific toxin gene. Nature 352: 82–85.
    Tomalski MD and Miller LK (1991) Insect paralysis by baculovirus mediated expression of mite neurotoxin gene. Nature 352: 82–85.
    book Weeden CR, Shelton AM and Hoffman MP (2000) Biological Control: A Guide to Natural Enemies in North America. Cornell University. http://www.nysaes.cornell.edu/ent/biocontrol/.
 Further Reading
    book Acosta EW (2005) List of Beneficial Insects, Mites and Organisms. Brentwood, TN: Biocontrol Network. http://www.biconet.com/biocontrol.html
    book Copping LG (2001) The Biopesticide Manual: A World Compendium of Naturally Occurring Biopesticides. Bracknell: BCPC Publications.
    book Hall FR and Menn JJ (eds) (1998) Biopesticides: Use and Delivery. Totowa, NJ: Humana Press.
    other Legner E (2005) Biological-integrated Pest Control & Insect Identification: The Biological and Integrated Control of Pest Arthropods, Weeds and Vertebrates Emphasizing the Classical Approach by the Use of Imported Natural Enemies. http://www.faculty.ucr.edu/~legneref/..
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How to Cite close
Harper, David R(Apr 2006) Biological Control by Microorganisms. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0004334]