Bacterial Genomes

Ronald M Atlas, University of Louisville, Louisville, Kentucky, USA
Daniel Drell, US Department of Energy, Washington DC, USA
Claire Fraser, The Institute for Genomic Research, Rockville, Maryland, USA

Published online: April 2001

DOI: 10.1038/npg.els.0000446

The genomes of a number of bacterial species have been fully sequenced. Analyses of these genomes are providing useful insights into the evolution and functioning of diverse bacteria and bacterial pathogens.

Keywords: bacteria; microorganisms; pathogens

Figure 1. Functional distribution of genes for the bacterium Aquifex aeolicus VF5.
Figure 2. Functional distribution of genes for the bacterium Thermotoga maritima MSB8.
Figure 3. Functional distribution of genes for the bacterium Synechocystis sp. PCC 6803.
Figure 4. Functional distribution of genes for the bacterium Haemophilus influenzae KW20.
Figure 5. Functional distribution of genes for the bacterium Mycoplasma genitalium G-37KW20.
Figure 6. Functional distribution of genes for the bacterium Treponema pallidum Nichols.
Figure 7. Functional distribution of genes for the bacterium Helicobacter pylori 26695.
Figure 8. Functional distribution of genes for the bacterium Mycobacterium tuberculosis CSU 93.
close
 References
    Alm RA, Ling LS, Moir DT et al. (1999) Genomic-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori. Nature 397: 176–180.
    Andersson SG, Zomorodipour A, Andersson JO et al. (1998) The genome sequence of Rickettsia prowazekii and the origin of mitochondria. Nature 396: 133–140.
    Blattner FR, Plunkett G III, Bloch CA et al. (1997) The complete genome sequence of Escherichia coli K-12. Science 277: 1453–1474.
    Casjens S, Palmer N, van Vugt R et al. (2000) A bacterial genome in flux: the twelve linear and nine circular extrachromosomal DNAs in an infectious isolate of the Lyme disease spirochete Borrelia burgdorferi. Molecular Microbiology 35: 490–516.
    Cole ST, Brosch R, Parkhill J et al. (1998) Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 393: 537–544.
    Deckert G, Warren PV, Gaasterland T et al. (1998) The complete genome of the hyperthermophilic bacterium Aquifex aeolicus. Nature 392: 353–358.
    Fleischmann RD, Adams MD, White O et al. (1995) Whole-genome random sequencing and assembly of Haemophilus influenzae Rd. Science 269: 496–512.
    Fraser CM, Gocayne JD, White O et al. (1995) The minimal gene complement of Mycoplasma genitalium. Science 270: 397–403.
    Fraser CM, Casjens S, Huang WM et al. (1997) Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi. Nature 390: 580–586.
    Fraser CM, Norris SJ, Weinstock GM et al. (1998) Complete genome sequence of Treponema pallidum, the syphilis spirochete. Science 281: 375–388.
    Heidelberg JF, Eisen JA, Nelson WC et al. (2000) DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae. Nature 406: 477–483.
    Himmelreich R, Hilbert H, Plagens H et al. (1996) Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae. Nucleic Acids Research 24: 4420–4449.
    Hutchison CA III, Peterson SN, Gill SR et al. (1999) Global transposon mutagenesis and a minimal Mycoplasma genome. Science 286: 2165–2169.
    Kalman S, Mitchell W, Marathe R et al. (1999) Comparative genomes of Chlamydia pneumoniae and C. trachomatis. Nature Genetics 21: 385–389.
    Kaneko T, Sato S, Kotani H et al. (1996) Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions. DNA Research 3: 109–136.
    Kunst F, Ogasawara N, Moszer I et al. (1997) The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Nature 390: 249–256.
    Nelson KE, Clayton RA, Gill SR et al. (1999) Evidence for lateral gene transfer between Archaea and bacteria from genome sequence of Thermotoga maritima. Nature 399: 323–329.
    Nicole TP, Plunkett G, Burland V et al. (2001) Genome sequence of enterohaemorrhagic Escherichia coli O157:H7. Nature 409: 529–533.
    Parkhill J, Wren BW, Mungall K et al. (2000) The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences. Nature 403: 665–668.
    Read TD, Brunham RC, Shen C et al. (2000) Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39. Nucleic Acids Research 28: 1397–1406.
    Simpson AJG, Reinach FC, Arruda P et al. (2000) The genome sequence of the plant pathogen Xylella fastidiosa. Nature 406: 151–157.
    Stephens RS, Kalman S, Lammel C et al. (1998) Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis. Science 282: 754–759.
    Tettelin H, Saunders NJ, Heidelberg J et al. (2000) Complete genome sequence of Neisseria meningitidis serogroup B strain MC58. Science 287: 1809–1815.
    Tomb JF, White O, Kerlavage AR et al. (1997) The complete genome sequence of the gastric pathogen Helicobacter pylori. Nature 388: 539–547.
    White O, Eisen JA, Heidelberg JF et al. (1999) Genome sequence of the radioresistant bacterium Deinococcus radiodurans R1. Science 286: 1571–1577.

Related Sub-Topics:

Evolutionary Genomics | Evolutionary Ecology | Bacteria | Genomes and Chromosomes | Medical Microbiology | Microbial Evolution and Taxonomy
Contact Editor close
Submit a note to the editor about this article by filling in the form below.

* Required Field

Article Title: Bacterial Genomes
 
How to Cite close
Atlas, Ronald M, Drell, Daniel, and Fraser, Claire(Apr 2001) Bacterial Genomes. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0000446]