Immunity to Bacteria

Abstract

Bacterial infections cause a variety of immune responses from the host depending on the specific bacterium involved. Understanding the virulence of bacteria provides insight into the medical approaches that can be used to treat infection and prevent disease.

Keywords: infectious disease; immune response; immune evasion; mechanisms of disease; mechanisms of host defence

Figure 1.

Schematic representation of the role of antibody and opsonization. (a) Antibody (yellow) binds to antigenic components on a bacterial surface (red). (b) The Fc region of the antibody becomes bound by Fc receptors expressed on a phagocyte (blue). (c) The phagocyte engulfs the bacterial cell through endocytosis. (d) The eventual fusion of the phagosome with intracellular lysosomes will both digest the pathogen and process bacterial antigens for presentation to the immune system.

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Further Reading

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How to Cite close
Lowe, Devin B, Shearer, Michael H, Jumper, Cynthia A, and Kennedy, Ronald(Jul 2007) Immunity to Bacteria. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1002/9780470015902.a0000481.pub2]