Cerebral Cortex Development
Magdalena Götz, Max‐Planck Institute of Neurobiology, Munich, Germany
Published online: April 2001
DOI: 10.1038/npg.els.0000787
Abstract
In the developing cerebral cortex, some aspects of neuronal phenotype are specified even before neurogenesis, whereas others
remain plastic for some time postnatally. The combination of early specification and later plasticity creates the multitude
of cell types in the cerebral cortex.
Keywords: neurogenesis; patterning; cortical layers; cell fate; cortical area; axonal pathfinding
Further Reading
Bayer S and
Altman J
(1991)
Neocortical Development.
New York: Raven Press.
Bolz J,
Götz M,
Hübener M and
Novak N
(1993)
Reconstructing cortical connections in a dish.
Trends in Neurosciences
16: 310–316.
Kennedy H and
Dehay C
(1991)
The cortex of mice and men.
Cerebral Cortex
3: 171–186.
Levitt P,
Barbe MF and
Eagleson KL
(1997)
Patterning and specification of the cerebral cortex.
Annual Review of Neuroscience
20: 1–24.
McConnell SK
(1995)
Strategies for the generation of neuronal diversity in the developing central nervous system.
Journal of Neuroscience
15(11): 6987–6998.
Rakic P
(1988)
Specification of cerebral areas.
Science
241: 170–176.
Reichert H and
Boyan G
(1997)
Building a brain: developmental insights in insects.
Trends in Neurosciences
20: 258–264.