Transfer RNA
Emanuel Goldman, New Jersey Medical School, Newark, New Jersey, USA
Published online: September 2008
DOI: 10.1002/9780470015902.a0000878.pub2
Abstract
Transfer ribonucleic acid (tRNA) is the class of molecules that decode the genetic code and link the coded information to
their attached amino acids. These become constituents of the protein specified by the gene.
Keywords: protein synthesis; genetic code; ribosomes; aminoacylation
Further Reading
Agris PF,
Vendeix FA and
Graham WD
(2007)
tRNA's wobble decoding of the genome: 40 years of modification.
Journal of Molecular Biology
366:
1–13.
Bjork GR
(1995)
Genetic dissection of synthesis and function of modified nucleosides in bacterial transfer RNA.
Progress in Nucleic Acid Research and Molecular Biology
50:
263–338.
Eggertsson G and
Söll D
(1988)
Transfer ribonucleic acid‐mediated suppression of termination codons in E. coli.
Microbiological Reviews
52:
354–374.
Giegé R,
Sissler M and
Florentz C
(1998)
Universal rules and idiosyncratic features in tRNA identity.
Nucleic Acids Research
26:
5017–5035.
Goldman E and
Jakubowski H
(1990)
Uncharged tRNA, protein synthesis, and the bacterial stringent response.
Molecular Microbiology
4:
2035–2040.
Journal of Biosciences
(2006)
History of tRNA Research.
Journal of Biosciences
31:
437–496. http://www.ias.ac.in/jbiosci/oct2006/contents.htm.
Parker J
(1989)
Errors and alternatives in reading the universal genetic code.
Microbiological Reviews
53:
273–298.
RajBhandary UL
(1994)
Initiator transfer RNAs.
Journal of Bacteriology
176:
547–552.
Rich A and
RajBhandary UL
(1976)
Transfer RNA: molecular structure, sequence and properties.
Annual Review of Biochemistry
45:
805–860.
Schimmel PR,
Söll D and
Abelson JN (eds)
(1979)
Transfer RNA: Structure, Properties and Recognition.
Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
Söll D,
Abelson JN and
Schimmel PR (eds)
(1980)
Transfer RNA: Biological Aspects.
Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
Söll D and
RajBhandary UL (eds)
(1995)
tRNA.
Washington, DC: American Society for Microbiology.
Wilson DN and
Nierhaus KH
(2006)
The E‐site story: the importance of maintaining two tRNAs on the ribosome during protein synthesis.
Cellular and Molecular Life Sciences
63:
2725–2737.