Antiserum

Delia Margaret Goodall, University of Birmingham Medical School, Birmingham, UK
Chandra Raykundalia, University of Birmingham Medical School, Birmingham, UK

Published online: April 2001

DOI: 10.1038/npg.els.0000911

Antiserum is a general term used to denote the noncellular component of blood (serum) containing a mixture of antibodies (polyclonal), the donor usually having been actively immunized with a known antigen.

Keywords: antigen; antibody; immunization; monoclonal; polyclonal

 References
    book Catty D and Raykundalia C (1988) "Production and quality control of polyclonal antibodies". In: Catty D (ed.) Antibodies, vol. I, A Practical Approach. Oxford: IRL Press.
    Galfré G and Milstein C (1981) Preparation of monoclonal antibodies: strategies and procedures. Methods in Enzymology 73: 1–46.
    book Green JA and Manson MM (1998) "Production of polyclonal antisera". In: Pound J (ed.) Immunochemical Protocols, 2nd edn, pp. 1–13. Totowa, NJ: Humana Press.
    Köhler G and Milstein C (1975) Continuous culture of fused cells secreting antibody of predefined specificity. Nature 256: 495–497.
    book Stewart-Tull DES (1997a) The Choice and Mechanism of Action of Adjuvants. Switzerland: Horwood Academic Publications.
    book Stewart-Tull DES (1997b) "The use of adjuvants in the production of polyclonal antisera to protein antigens". In: van Zutphen LFM and Balls M (eds) Animal Alternatives, Welfare and Ethics: Developments in Animal and Veterinary Sciences, vol. 27, pp. 989–994. Amsterdam: Elsevier.
 Further Reading
    book Catty D (ed.) (1988) Antibodies, vol. I, A Practical Approach. Oxford: IRL Press.
    book Catty D (ed.) (1989) Antibodies, vol. II, A Practical Approach. Oxford: IRL Press.
    book Goding JW (1996) Monoclonal Antibodies: Principles and Practice, 3rd edn. London: Academic Press.
    book Pound JD (ed.) (1998) Immunochemical Protocols, 2nd edn. Methods in Molecular Biology, vol. 80. Totowa, NJ: Humana Press.

Related Sub-Topics:

Antibodies | Antigens
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Article Title: Antiserum
 
How to Cite close
Goodall, Delia Margaret, and Raykundalia, Chandra(Apr 2001) Antiserum. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0000911]