Rodney D Berg, Louisiana State University, Shreveport, Louisiana, USA
Published online: April 2001
DOI: 10.1038/npg.els.0000941
The indigenous gastrointestinal microflora consists of microorganisms that normally inhabit the gastrointestinal tract. The indigenous microflora primes the host immune response so that it can respond more effectively to exogenous pathogens.
Keywords: GI microflora; indigenous microflora; indigenous bacteria; gastrointestinal bacteria; natural antibodies; immunostimulation by indigenous bacteria; bacterial translocation; opportunistic infections
| References | |
| book Berg RD (1983a) "The immune response to indigenous intestinal bacteria". In: Hentges D (ed.) The Intestinal Microflora in Health and Disease, New York: Academic Press, pp. 101–126. | |
| book Berg RD (1983b) "Translocation of indigenous bacteria from the intestinal tract". In: Hentges D (ed.) The Intestinal Microflora in Health and Disease, New York: Academic Press, pp. 333–352. | |
| book Berg RD (1992) "Translocation and the indigenous gut flora". In: Fuller R (ed.) Probiotics. The Scientific Basis, London: Chapman and Hall, pp. 55–85. | |
| Berg RD (1995) Bacterial translocation from the gastrointestinal tract. Trends in Microbiology 3: 149–154. | |
| book Berg RD (1998) "Translocation of microbes from the intestinal tract". In: Tannock GW (ed.) Medical Importance of Normal Microflora, pp. 338–370, London: Chapman and Hall. | |
| Berg RD and Garlington AW (1979) Translocation of certain indigenous bacteria from the gastrointestinal tract to the mesenteric lymph nodes and other organs in a gnotobiotic mouse model. Infection and Immunity 23: 403–411. | |
| Berg RD and Savage DC (1975) Immune response of specific pathogen-free and gnotobiotic mice to antigens of indigenous and nonindigenous microorganisms. Infection and Immunity 11: 320–329. | |
| Brown JF and Balish E (1978) Gastrointestinal microecology of BALB/c mice. Applied and Environmental Microbiology 36: 144–159. | |
| Brown WR, Savage DC, Dubois RS et al. (1972) Intestinal microflora of immunoglobulin-deficient and normal human subjects. Gastroenterology 62: 1143–1152. | |
| Dubos R, Schaedler RW, Costello R and Hoet P (1967) Indigenous normal and autochthonous flora of the gastrointestinal tract. Journal of Experimental Medicine 122: 67–78. | |
| book Kim YB, Setcavage TM, Kim DJ, Chun HG and Scheffel JW (1979) "Ontogenic development and differentiation of the immune system in the gnotobiotic miniature swine". In: Fleidner TM, Heit H, Neithammer D and Pfeiger H (eds) Clinical and Experimental Gnotobiotics, pp. 203–213 Stuttgart: Fischerl. | |
| Moore WEC and Holdeman LV (1974) Human fecal flora: the normal flora of 20 Japanese-Hawaiians. Applied Microbiology 27: 961–979. | |
| Robinet HG (1962) Relationship of host antibody to fluctuation of Escherichia coli serotypes in the human intestine. Journal of Bacteriology 84: 869–901. | |
| book Savage DC (1977a) "Interactions between the host and its microbes". In: Clarke RTJ and Bauchop T (eds) Microbial Ecology of the Gut, London: Academic Press, pp. 277–310. | |
| book Savage DC (1977b) "Associations of indigenous microorganisms with gastrointestinal epithelial surfaces". In: Hentges DJ (ed.) Human Intestinal Microflora in Health and Disease, pp. 55–78, New York: Academic Press. | |
| Shedlofsky S and Freter R (1974) Synergism between ecologic and immunologic control mechanisms of intestinal flora. Journal of Infectious Diseases 129: 296–303. | |
| Springer GF (1970) Importance of blood-group substances in interactions between man and microbes. Annals of the New York Academy of Sciences 169: 134–152. | |
| book Wostmann BS (1996) Germfree and Gnotobiotic Animal Models Background and Applications. Boca Raton, Florida: CRC Press. | |
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