Prokaryotic DNA‐binding Proteins

Abstract

DNA‐binding proteins are found in all organisms and play critical roles in DNA metabolism. Structure–function studies can be carried out on single‐strand specific binding proteins (SSBs), which function in DNA replication, recombination and repair.

Keywords: DNA‐binding protein; single‐strand specific binding protein; protein domains; protein–protein interaction; cooperativity

Figure 1.

Domain structure of gene 32 protein. *I is the truncated product created by the loss of the N‐terminal (‘B’) domain; *II is the truncated product created by the C‐terminal (‘A’) domain; *III, the core domain, is created by loss of both terminal domains.

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References

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Karpel, Richard L(Apr 2001) Prokaryotic DNA‐binding Proteins. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0001042]