Marburg virus is a typical emerging virus that causes severe haemorrhagic fever in humans, with high case-fatality rates.
Keywords: Marburg virus; filovirus; epidemiology; haemorrhagic fever; molecular biology
Marburg virus
Heinz Feldmann, Canadian Science Centre for Human and Animal Health, Winnipeg, Canada
Hans‐Dieter Klenk, Philipps University, Marburg, Germany
Published online: January 2003
DOI: 10.1038/npg.els.0001076
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Figure 1. The possible role of macrophages and endothelial cells in the development of haemorrhagic fever caused by Marburg virus. BM, basement membrane; CAM, cell adhesion molecule; E, erythrocyte; EC, endothelial cell; MAC, macrophage; N, nucleus; V, vacuole; Vir, virus particle. Adapted from Feldmann and Klenk (1996).
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| Further Reading | |
| Feldmann H and Klenk H-D (1996) Filoviruses: Marburg and Ebola. Advances in Virus Research 47: 1–52. | |
| book Feldmann H, Sanchez A and Klenk H-D (1998) "Filoviruses". In: Collier L et al. (eds) Topley and Wilson's Microbiology and Microbial Infections, 9th ed, vol. 1, pp. 651–664. London: Arnold. | |
| book Klenck H-D (ed.) (1999) "Marburg and Ebola viruses". Current Topics in Microbiology and Immunology 235 (in press). | |
| book Martini GA and Siegert R (eds) (1971) Marburg Virus Disease. New York: Springer Verlag. | |
| book Peters CJ, Sanchez A, Rollin PE, Ksiazek TG and Murphy FA (1996) "Filoviridae: Marburg and Ebola viruses". In: Fields BN, Knipe DM and Howley PM et al. (eds) Fields Virology, 3rd edn, pp. 1161–1176. Philadelphia: Lippincott-Raven. | |
