Yellow Fever Virus

Abstract

Yellow fever virus is a flavivirus that causes the disease yellow fever. The virus is found in tropical South America and subSaharan Africa. The disease varies from a febrile illness to a lethal haemorrhagic fever.

Keywords: yellow fever; arbovirus; flavivirus; haemorrhagic fever

Figure 1.

Organization of the flavivirus genome and expression of proteins (genes are not drawn to scale).

Figure 2.

Geographic areas in (a) Africa and (b) South America where yellow fever disease has been reported (shown in lilac). Not all areas have continual yellow fever disease.

Figure 3.

Transmission cycles of Yellow fever virus. The virus is transmitted between vertebrate hosts by various species of mosquitoes. The jungle (or sylvatic) cycle (a) involves monkeys and tree hole‐breeding mosquitoes; the urban cycle (b) involves humans and the Aedes aegypti mosquito.

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References

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Further Reading

Augustin G (1909) History of Yellow Fever. New Orleans: Searcy and Pfaff.

Monath TP (ed.) (1988) Yellow fever. In: The Arboviruses: Ecology and Epidemiology, ,pp. 139–231. Boca Raton: CRC Press

Monath TP (1991) Yellow fever: Victor, Victoria? Conqueror, conquest? Epidemics and research in the last forty years and prospects for the future. American Journal of Tropical Medicine and Hygiene 45: 1–43.

Monath TP (1998) Yellow fever. In: Plotkin SA and Orenstein WA (eds) Vaccines, 3rd edn, ,pp. 815–879. Philadelphia: WB Saunders

Monath TP and Heinz FX (1996) Flaviviruses. In: Fields BN, Knipe DM and Howley PM (eds) Fields Virology, 3rd edn, ,pp. 961–1034. Philadelphia: Lippincott‐Raven

Rice CM (1996) Flaviviridae: the viruses and their replication. In: Fields BN, Knipe DM and Howley PM (eds) Fields Virology, 3rd edn, pp. 931–960. Philadelphia: Lippincott‐Raven

Tomari O (1999) Impact of yellow fever on the developing world. Advances in Virus Research 53: 5–34.

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How to Cite close
Barrett, Alan DT(Jul 2003) Yellow Fever Virus. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0001094]