Miodrag L Lukic, UAE University, Al‐Ain, United Arab Emirates
Aleksandra M Lukic, University of Belgrade, Belgrade, Yugoslavia
Published online: April 2002
DOI: 10.1038/npg.els.0001133
Early events in an immune response may determine the outcome of immunogenic stimulus, and molecules produced as part of an immune response - such as cytokines and antibodies - can feed back into, suppress or promote the response. Both under- and overreaction to antigens may be deleterious, so the immune system requires control mechanisms at different levels so as to provide an optimal immune response at all times.
Keywords: antigen; immune responsiveness; cytokines; T
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