Klaus Kratochwil, Institute of Molecular Biology, Salzburg, Austria
Published online: April 2001
DOI: 10.1038/npg.els.0001141
Epithelial-mesenchymal organs develop through sequential and reciprocal interaction of the two tissues. A limited set of signalling factors mediates this interaction in a variety of organ systems.
Keywords: epithelium; mesenchyme; tissue interaction; organogenesis; signal factors; intercellular signalling
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| Further Reading | |
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| Martinez Arias A, Brown AMC and Brennan K (1999) Wnt signalling: pathway or network? Current Opinion in Genetics and Development 9: 447–454. | |
| Massagué J and Chen Y-G (2000) Controlling TGF- signaling. Genes and Development 14: 627–644. | |
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| Thesleff I and Sharpe P (1997) Signalling networks regulating dental development. Mechanisms of Development 67: 111–123. | |
| ePath Wnt gene homepage: ePath [http://www.stanford.edu/~rnusse/wntwindow.html] or ePath [http://www.ana.ed.ac.uk/rnusse/wntwindow.html] | |
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