| References |
|
|
Arango NA,
Lovell-Badge R and
Behringer RR
(1999)
Targeted mutagenesis of the endogenous mouse Mis gene promoter: in vivo definition of genetic pathways of vertebrate sexual development.
Cell
99:
409419.
|
|
|
Barrionuevo F,
Bagheri-Fam S,
Klattig J et al.
(2006)
Homozygous inactivation of Sox9 causes complete XY sex reversal in mice.
Biology of Reproduction
74:
195201.
|
|
|
Barsoum IB and
Yao HH
(2010)
Fetal Leydig cells: progenitor cell maintenance and differentiation.
Journal of Andrology
31:
1115.
|
|
|
Bowles J,
Feng CW,
Spiller C et al.
(2010)
FGF9 suppresses meiosis and promotes male germ cell fate in mice.
Develeopmental Cell
19:
440449.
|
|
|
Bowles J,
Knight D,
Smith C et al.
(2006)
Retinoid signaling determines germ cell fate in mice.
Science
312:
596600.
|
|
|
Bowles J,
Schepers G and
Koopman P
(2000)
Phylogeny of the SOX family of developmental transcription factors based on sequence and structural indicators.
Developmental Biology
227:
239255.
|
|
|
Bradford ST,
Hiramatsu R,
Maddugoda MP et al.
(2009)
The cerebellin 4 precursor gene is a direct target of SRY and SOX9 in mice.
Biology of Reproduction
80:
11781188.
|
|
|
Brennan J,
Karl J and
Capel B
(2002)
Divergent vascular mechanisms downstream of Sry establish the arterial system in the XY gonad.
Developmental Biology
244:
418428.
|
|
|
Bridges CB and
Anderson EG
(1925)
Crossing over in the X Chromosomes of Triploid Females of DROSOPHILA MELANOGASTER.
Genetics
10:
418441.
|
|
|
Bullejos M and
Koopman P
(2001)
Spatially dynamic expression of Sry in mouse genital ridges.
Developmental Dynamics
221:
201205.
|
|
|
Bullejos M and
Koopman P
(2004)
Germ cells enter meiosis in a rostro-caudal wave during development of the mouse ovary.
Molecular Reproduction and Development
68:
422428.
|
|
|
Capel B,
Albrecht KH,
Washburn LL and
Eicher EM
(1999)
Migration of mesonephric cells into the mammalian gonad depends on Sry.
Mechanisms of Development
84:
127131.
|
|
|
Caricasole A,
Duarte A,
Larsson SH et al.
(1996)
RNA binding by the Wilms tumor suppressor zinc finger proteins.
Proceedings of the National Academy of Sciences of the USA
93:
75627566.
|
|
|
Chaboissier MC,
Kobayashi A,
Vidal VIP et al.
(2004)
Functional analysis of Sox8 and Sox9 during sex determination in the mouse.
Development
131:
18911901.
|
|
|
Chassot AA,
Ranc F,
Gregoire EP et al.
(2008)
Activation of beta-catenin signaling by Rspo1 controls differentiation of the mammalian ovary.
Human Molecular Genetics
17:
12641277.
|
|
|
Chiquoine AD
(1954)
The identification, origin, and migration of the primordial germ cells in the mouse embryo.
Anatomical Record
118:
135146.
|
|
|
Combes AN,
Lesieur E,
Harley VR et al.
(2009a)
Three-dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development.
Developmental Dynamics
238:
10331041.
|
|
|
Combes AN,
Wilhelm D,
Davidson T et al.
(2009b)
Endothelial cell migration directs testis cord formation.
Developmental Biology
326:
112120.
|
|
|
Dolci S and
De Felici M
(1990)
A study of meiosis in chimeric mouse fetal gonads.
Development
109:
3740.
|
|
|
Eicher EM,
Washburn LL,
Schork NJ et al.
(1996)
Sex-determining genes on mouse autosomes identified by linkage analysis of C57BL/6J-YPOS sex reversal.
Nature Genetics
14:
206209.
|
|
|
Giese K,
Pagel J and
Grosschedl R
(1994)
Distinct DNA-binding properties of the high mobility group domain of murine and human SRY sex-determining factors.
Proceedings of the National Academy of Sciences of the USA
91:
33683372.
|
|
|
Hammes A,
Guo JK,
Lutsch G et al.
(2001)
Two splice variants of the Wilms' tumor gene have distinct functions during sex determination and nephron formation.
Cell
106:
319329.
|
|
|
Jost A
(1947)
Recherches sur la différenciation sexuelle de l'embryon de lapin. III. Rôle des gonades foetales dans la différenciation sexuelle somatique.
Archives d'Anatomie Microscopique et de Morphologie Experimentale
36:
271315.
|
|
|
Kim Y,
Kobayashi A,
Sekido R et al.
(2006)
Fgf9 and Wnt4 act as antagonistic signals to regulate mammalian sex determination.
PLoS Biology
4:
e187.
|
|
|
Koopman P,
Gubbay J,
Vivian N,
Goodfellow P and
Lovell-Badge R
(1991)
Male development of chromosomally female mice transgenic for SRY.
Nature
351:
117121.
|
|
|
Koubova J,
Menke DB,
Zhou Q et al.
(2006)
Retinoic acid regulates sex-specific timing of meiotic initiation in mice.
Proceedings of the National Academy of Sciences of the USA
103:
24742479.
|
|
|
Kreidberg JA,
Sariola H,
Loring JM et al.
(1993)
WT-1 is required for early kidney development.
Cell
74:
679691.
|
|
|
Loffler KA,
Zarkower D and
Koopman P
(2003)
Etiology of ovarian failure in blepharophimosis ptosis epicanthus inversus syndrome: FOXL2 is a conserved, early acting gene in vertebrate ovarian development.
Endocrinology
144:
32373243.
|
|
|
Martineau J,
Nordqvist K,
Tilmann C,
Lovell-Badge R and
Capel B
(1997)
Male-specific cell migration into the developing gonad.
Current Biology
7:
958968.
|
|
|
Morais da Silva S,
Hacker A,
Harley V et al.
(1996)
Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birds.
Nature Genetics
14:
6268.
|
|
|
Parma P,
Pailhoux E and
Cotinot C
(1999)
Reverse transcription-polymerase chain reaction analysis of genes involved in gonadal differentiation in pigs.
Biology of Reprodruction
61:
741748.
|
|
|
Pontiggia A,
Rimini R,
Harley VR et al.
(1994)
Sex-reversing mutations affect the architecture of SRY-DNA complexes.
EMBO Journal
13:
61156124.
|
|
|
de Santa Barbara P,
Bonneaud N,
Boizet B et al.
(1998)
Direct interaction of SRY-related protein SOX9 and steroidogenic factor 1 regulates transcription of the human anti-Müllerian hormone gene.
Molecular and Cellular Biology
18:
66536665.
|
|
|
Schmahl J,
Eicher E,
Washburn L and
Capel B
(2000)
Sry induces cell proliferation in the mouse gonad.
Development
127:
6573.
|
|
|
Sekido R and
Lovell-Badge R
(2008)
Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer.
Nature
453:
930934.
|
|
|
Sekido R,
Bar I,
Narvaez V,
Penny G and
Lovell-Badge R
(2004)
SOX9 is up-regulated by the transient expression of SRY specifically in Sertoli cell precursors.
Developmental Biology
274:
271279.
|
|
|
Sinclair AH,
Berta P,
Palmer MS et al.
(1990)
A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif.
Nature
346:
240244.
|
|
|
Swain A,
Narvaez V,
Burgoyne PS,
Camerino G and
Lovell-Badge R
(1998)
Dax1 antagonizes SRY action in mammalian sex determination.
Nature
391:
761767.
|
|
|
Tomizuka K,
Horikoshi K,
Kitada R et al.
(2008)
R-spondin1 plays an essential role in ovarian development through positively regulating Wnt-4 signaling.
Human Molecular Genetics
17:
12781291.
|
|
|
Vainio S,
Heikkila M,
Kispert A,
Chin N and
McMahon AP
(1999)
Female development in mammals is regulated by Wnt-4 signalling.
Nature
397:
405409.
|
|
|
Wilhelm D and
Englert C
(2002)
The Wilms tumor suppressor WT1 regulates early gonad development by activation of Sf1.
Genes & Development
16:
18391851.
|
|
|
Wilhelm D,
Hiramatsu R,
Mizusaki H et al.
(2007)
SOX9 regulates prostaglandin D synthase gene transcription in vivo to ensure testis development.
Journal of Biological Chemistry
282:
1055310560.
|
|
|
Wilson MJ,
Jeyasuria P,
Parker KL and
Koopman P
(2005)
The transcription factors steroidogenic factor-1 and SOX9 regulate expression of Vanin-1 during mouse testis development.
Journal of Biological Chemistry
280:
59175923.
|
|
|
Yu RN,
Ito M,
Saunders TL,
Camper SA and
Jameson JL
(1998)
Role of Ahch in gonadal development and gametogenesis.
Nature Genetics
20:
353357.
|
|
|
Zanaria E,
Muscatelli F,
Bardoni B et al.
(1994)
An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita.
Nature
372:
635641.
|
| Further Reading |
|
|
Brennan J and
Capel B
(2004)
One tissue, two fates: molecular genetic events that underlie testis versus ovary development.
Nature Reviews Genetics
5:
509521.
|
|
|
Koopman P
(1999)
Sry and Sox9: mammalian testis-determining genes.
Cellular and Molecular Life Sciences
55:
839856.
|
|
|
McLaren A
(2003)
Primordial germ cells in the mouse.
Developmental Biology
262:
115.
|
|
|
Wilhelm D and
Koopman P
(2006)
The makings of maleness: towards an integrated view of male sexual development.
Nature Reviews Genetics
7:
620631.
|
|
|
Wilhelm D,
Palmer S and
Koopman P
(2007)
Sex determination and gonadal development in mammals.
Physiological Reviews
87:
128.
|