Immune System: Manipulation In Vivo

Abstract

The immune system is manipulated by procedures aimed at potentiating immune responses to cope efficiently with antigenic and microbial challenges or to inhibit tumour development. However, suppression or re‐education of the immune system is an essential strategy to control undesired immune reactions directed either to self or to transplanted antigens.

Keywords: immunomodulation; immunostimulants; immunotherapy

References

Arca MJ, Muli JJ and Chany AE (1996) Genetic approaches to adoptive cellular therapy of malignancy. Seminars in Oncology 23: 108–117.

Beissert S and Granstein RD (1995) UV‐induced cutaneous photobiology. Critical Reviews in Biochemistry and Molecular Biology 31: 381–404.

Dalakas MC (1997) Intravenous immune globulin therapy for neurologic diseases. Annals of Internal Medicine 126: 721–730.

Liles WC and Van Voorhis WC (1995) Review: nomenclature and biologic significance of cytokines involved in inflammation and the host immune response. Journal of Infectious Diseases 172: 1573–1580.

Liu MA (1998) Vaccine developments. Nature Medicine 4: 515–519.

Werner GH and Jollés P (1996) Immunostimulating agents: what next? A review of their present and potential medical applications. European Journal of Biochemistry 242: 1–19.

Wilson M, Seymour R and Henderson B (1998) Bacterial perturbation of cytokine networks. Infection and Immunity 66: 2401–2409.

Further Reading

Flake AW and Zanjani ED (1993) In utero transplantation of hematopoietic stem cells. Critical Reviews in Oncology/Hematology 15: 35–48.

Hadden JW (1993) Immunostimulants. Immunology Today 14: 275–280.

Kotzin BL, Leung DY, Kappler J and Marrack P (1993) Superantigens and their potential role in human disease. Advances in Immunology 54: 99–166.

Lee JH and Klein HG (1994) Mononuclear cell adoptive immunotherapy. Hematology/Oncology Clinics of North America 8: 1203–1221.

Nüssler AK and Thomson AW (1992) Immunomodulatory agents in the laboratory and clinic. Parasitology 105: S5–S23.

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How to Cite close
Bahr, George M(Apr 2001) Immune System: Manipulation In Vivo. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0001208]