Immunological Danger Signals

The conventional understanding of the immune system is that it can differentiate self from nonself. In contrast, the danger theory proposes that the immune system does not react to foreign substances but instead responds to situations that are potentially harmful.

Keywords: danger; autoimmunity; tolerance; tumour; transplantation

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Monestier, Marc(May 2002) Immunological Danger Signals. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0001210]