Myeloid Cell Differentiation


Myeloid cell differentiation is the process by which stem cells develop into various types of mature blood cell. This is achieved by the sequential activation of sets of genes, which produce the proteins that direct cell development and confer the specific properties of blood cells. Disruption of this process is believed to result in leukaemia.

Keywords: myeloid; differentiation; leukaemia; translocation

Figure 1.

The steps of myeloid cell differentiation, from pluripotent stem cell to differentiated cells. Transcription factors identified as necessary for a specific stage of differentiation are indicated.



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Further Reading

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How to Cite close
Biggs, Joseph R, and Kraft, Andrew S(Apr 2001) Myeloid Cell Differentiation. In: eLS. John Wiley & Sons Ltd, Chichester. [doi: 10.1038/npg.els.0001218]