Protein–RNA Interactions


RNA–protein interactions play important roles in many biological processes. The basic features of RNA and proteins that contribute to specific recognition of RNA by proteins are currently being elucidated.

Keywords: RNA structure; protein motifs; ribonucleoprotein motif; arginine‐rich motif; double‐stranded RNA‐binding domain; K homology motif; RGG motif

Further Reading

Arnez JG and Cavarelli J (1997) Structures of RNA‐binding proteins. Quarterly Reviews of Biophysics 30: 195–240.

Burd CG and Dreyfuss G (1994) Conserved structures and diversity of functions of RNA‐binding proteins. Science 265: 615–621.

Draper DE (1995) Protein–RNA recognition. Annual Review of Biochemistry 64: 593–620.

Gesteland RF and Atkins JF (eds) (1993) The RNA World: the Nature of Modern RNA Suggests a Prebiotic RNA World. Plainview: Cold Spring Harbor Laboratory Press.

Mattaj IW (1993) RNA recognition: a family matter? Cell 73: 837–840.

Ramakrishnan V and White SW (1998) Ribosomal protein structures: insights into the architecture, machinery and evolution of the ribosome. Trends in Biochemical Science 23: 208–212.

Siomi H and Dreyfuss G (1997) RNA‐binding proteins as regulators of gene expression. Current Opinion in Genetics and Development 7: 345–353.

Nagai K and Mattaj IW (eds) (1994) RNA–Protein Interactions. Oxford: IRL Press.

Yonath A and Franceschi F (1997) New RNA recognition features revealed in ancient ribosomal proteins. Nature Structural Biology 4: 3–5.

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How to Cite close
Houser‐Scott, Felicia, and Engelke, David R(Apr 2001) Protein–RNA Interactions. In: eLS. John Wiley & Sons Ltd, Chichester. [doi: 10.1038/npg.els.0001360]