Forensic Genetics

Abstract

The primary objective in forensic deoxyribonucleic acid DNA is to develop a useable genetic profile from a piece of evidence to compare with profiles obtained from reference samples from known individuals for the purpose of exclusion.

Keywords: crime site investigation (CSI); forensic DNA; short tandem repeat; DNA databanks

References

Alford RL, Hammond HA, Coto I and Caskey CT (1994) Rapid and efficient resolution of parentage by amplification of short tandem repeats. American Journal of Human Genetics 55: 190–195.

Budowle B, Moretti TR, Baumstark AL, Defenbaugh DA and Keys KM (1999) Population data on the thirteen CODIS core short tandem repeat loci in African Americans, US Caucasians, Hispanics, Bahamanians, Jamaicans and Trinidadians. Journal of Forensic Sciences 44: 1277–1286.

Budowle B, Moretti TR, Niezgoda SJ and Grown BL (1998) CODIS and PCR‐based short tandem repeat loci: law enforcement tools. In: Second European Symposium on Human Identification, Conference Abstract, pp. 73–88. Madison: Promega Corporation.

Cole S (2001) Suspect Identities : A History of Fingerprinting and Criminal Identification Cambridge: Harvard University Press

Edwards A, Civitello A, Hammond H and Caskey CT (1991) DNA typing and genetic mapping with trimeric and tetrameric tandem repeats. American Journal of Human Genetics 49: 746–756.

Farley MA and Harrington JJ (eds) (1991) Forensic DNA Technology. Chelsea, MI: Lewis Publishers, Inc.

Galton F (1892) Fingerprints. London: MacMillan.

Hammond HA, Zhong Y, Caskey CT and Chakraborty R (1994) Evaluation of 13 short tandem repeat loci for use in personal identification applications. American Journal of Human Genetics 55: 175–189.

Ju JY, Glazer AN and Mathies RA (1996) Energy transfer primers: a new fluorescence labeling paradigm for DNA sequencing and analysis. Nature Medicine 2: 246–249.

Kimmelman J (2000) The promise and perils of criminal DNA databanking. Nature Biotechnology 18: 695–696.

Ladd C, Adamowicz MS, Bourke MT, Scherczinger CA and Lee HC (1999) A systematic analysis of secondary DNA transfer. Journal of Forensic Sciences 44: 1270–1272.

Lander ES (1989) DNA fingerprinting on trial. Nature 339: 501–505.

Lander ES and Budowle B (1994) DNA fingerprinting dispute laid to rest. Nature 371: 735–738.

McEwen JE (1995) Forensic DNA data banking by state crime laboratories. American Journal of Human Genetics 56: 1487–1492.

McEwen JE and Reilly PR (1994) A review of state legislation on DNA forensic data banking. American Journal of Human Genetics 54: 941–958.

Mullis KB, Ferre F and Gibbs RA (eds) (1994) The Polymerase Chain Reaction. Boston, MA: Birkhauser Press.

Reynolds R, Sensabaugh G and Blake E (1991) Analysis of genetic markers in forensic DNA samples using the polymerase chain reaction. Analytical Chemistry 63: 2–15.

Saike R, Gelfand DH, Stoffel S et al. (1988) Primer‐directed enzymatic amplification of DNA with thermostable DNA polymerase. Science 239: 487–491.

Scheck B (1994) DNA data banking: a cautionary tale (invited editorial). American Journal of Human Genetics 54: 931–933.

Southern EM (1975) Detection of specific sequences among DNA fragments separated by gel electrophoresis. Journal of Molecular Biology 98: 503–517.

Sutherland G and Richards R (1994) Dynamic mutations. American Scientist 82: 157–163.

Venter JC, Adams MD, Meyers EW et al. (2001) The sequence of the human genome. Science 291(5507): 1304–1351.

Further Reading

Buckleton J, Triggs CM and Walsh SJ (2005) Forensic DNA Evidence Interpretation. Boca Raton, FL: CRC Press.

Butler J (2005) Forensic DNA Typing : Biology, Technology and Genetics of STR Markers, 2nd Burlington, MA: Elsevier Academic Press.

Evett IW and Weir BS (1998) Interpreting DNA Evidence: Statistical Genetics for Forensic Scientists. Sunderland, MA: Sinauer Publishers.

National Research Council (1996) The Evaluation of Forensic DNA Evidence. Washington, DC: National Academy Press.

Contact Editor close
Submit a note to the editor about this article by filling in the form below.

* Required Field

How to Cite close
Davis, Christie T(Jul 2007) Forensic Genetics. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1002/9780470015902.a0001466]