Mutation Rates: Data


Estimates of mutation rates from standard methods.

Keywords: mutation accumulation; substitution rate; inbreeding depression; deleterious mutation


Bulmer M, Wolfe KH and Sharp PM (1991) Synonymous nucleotide substitution rates in mammalian genes: implications for the molecular clock and the relationship of mammalian orders. Proceedings of the National Academy of Sciences of the USA 88: 5974–5978.

Drake JW, Charlesworth B, Charlesworth D and Crow JF (1998) Rates of spontaneous mutation. Genetics 148: 1667–1686.

Gaut BS (1998) Molecular clocks and nucleotide substitution rates in higher plants. Evolutionary Biology 30: 93–120.

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Schultz ST, Lynch M and Willis JH (1999) Spontaneous deleterious mutation in Arabidopsis thaliana. Proceedings of the National Academy of Sciences of the USA 96: 11393–11398.

Further Reading

Charlesworth B and Charlesworth D (1998) Some evolutionary consequences of deleterious mutations. Genetica 103: 3–19.

Crow JF (1997) The high spontaneous mutation rate: is it a health risk? Proceedings of the National Academy of Sciences of the USA 94: 8380–8386.

Crow JF and Simmons MJ (1983) The mutation load in Drosophila. In: Ashburner M, Carson HL and Thompson JN (eds) The Genetics and Biology of Drosophila, pp. 1–35. London: Academic Press.

Klekowski EJ (1988) Mutation, Developmental Selection, and Plant Evolution. New York: Columbia University Press.

Kondrashov AS (1998) Measuring spontaneous deleterious mutation process. Genetica 103: 183–197.

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Schultz, Stewart T(Jul 2003) Mutation Rates: Data. In: eLS. John Wiley & Sons Ltd, Chichester. [doi: 10.1038/npg.els.0001732]