Estimates of mutation rates from standard methods.
Keywords: mutation accumulation; substitution rate; inbreeding depression; deleterious mutation
Stewart T Schultz, University of Miami, Miami, Florida, USA
Published online: July 2003
DOI: 10.1038/npg.els.0001732
Estimates of mutation rates from standard methods.
Keywords: mutation accumulation; substitution rate; inbreeding depression; deleterious mutation
| References | |
| Bulmer M, Wolfe KH and Sharp PM (1991) Synonymous nucleotide substitution rates in mammalian genes: implications for the molecular clock and the relationship of mammalian orders. Proceedings of the National Academy of Sciences of the USA 88: 59745978. | |
| Drake JW, Charlesworth B, Charlesworth D and Crow JF (1998) Rates of spontaneous mutation. Genetics 148: 16671686. | |
| Gaut BS (1998) Molecular clocks and nucleotide substitution rates in higher plants. Evolutionary Biology 30: 93120. | |
| book Griffiths AJF, Miller JH, Suzuki DT, Lewontin RC and Gelbart WM (1996) An Introduction to Genetic Analysis. New York: WH Freeman. | |
| Keightley PD and Eyre-Walker A (1999) Terumi Mukai and the riddle of deleterious mutation rates. Genetics 153: 515523. | |
| Klekowski EJ (1998) Mutation rates in mangroves and other plants. Genetica 103: 325331. | |
| Lynch M, Blanchard J, Houle D et al. (1999) Perspective: spontaneous deleterious mutation. Evolution 53: 645663. | |
| book Sager R and Ryan FJ (1961) Cell Heredity. New York: John Wiley. | |
| Schultz ST, Lynch M and Willis JH (1999) Spontaneous deleterious mutation in Arabidopsis thaliana. Proceedings of the National Academy of Sciences of the USA 96: 1139311398. | |
| Further Reading | |
| Charlesworth B and Charlesworth D (1998) Some evolutionary consequences of deleterious mutations. Genetica 103: 319. | |
| Crow JF (1997) The high spontaneous mutation rate: is it a health risk? Proceedings of the National Academy of Sciences of the USA 94: 83808386. | |
| book Crow JF and Simmons MJ (1983) "The mutation load in Drosophila". In: Ashburner M, Carson HL and Thompson JN (eds) The Genetics and Biology of Drosophila, pp. 135. London: Academic Press. | |
| book Klekowski EJ (1988) Mutation, Developmental Selection, and Plant Evolution. New York: Columbia University Press. | |
| Kondrashov AS (1998) Measuring spontaneous deleterious mutation process. Genetica 103: 183197. | |