Multilocus population genetics is the study of the distribution and dynamics of genetic variation at several loci in biological populations.
Keywords: multilocus selection; linkage equilibrium; linkage disequilibrium; epistasis haplotype
Population Genetics: Multilocus
Max Shpak, University of Tennessee, Knoxville, Tennessee, USA
Sergey Gavrilets, University of Tennessee, Knoxville, Tennessee, USA
Published online: January 2006
DOI: 10.1038/npg.els.0004176
| References | |
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| Shpak M and Kondrashov AS (1999) The applicability of the hypergeometric phenotypic model to haploid and diploid populations. Evolution 53: 600–604. | |
| Shpak M, Stadler PF, Wagner GP and Hermisson J (2004) Aggregation of variables and system decomposition: applications to fitness landscape analysis. Theory in Biosciences 123: 33–68. | |
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| Turelli M and Barton NH (1990) Dynamics of polygenic characters under selection. Theoretical Population Biology 38: 1–57. | |
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| Further Reading | |
| Barton NH (2000) Estimating multilocus linkage disequilibrium. Heredity 84: 373–389. | |
| book Buerger R (2000) "The Mathematical Theory of Selection, Recombination, and Mutation". New York: Wiley. | |
| book Christiansen FB (1999) Population Genetics at Multiple Loci. NY: Wiley. | |
| book Crow JF and Kimura M (1970) Introduction to Population Genetics Theory. NY: Harper and Row. | |
| book Ewens WJ (2004) Mathematical Population Genetics. NY: Springer. | |
| book Hartl DL and Clark AG (1997) Principles of Population Genetics. Sunderland, MA: Sinauer. | |
| book Lewontin RC (1974) The Genetic Basis of Evolutionary Change. New York: Columbia University Press. | |
| book Nagylaki T (1992) Introduction to Theoretical Population Genetics. New York: Springer. | |
| book Rice SH (2004) Evolutionary Theory – Mathematical and Conceptual Foundations. Sunderland MA: Sinauer. | |
| book Svirezhev IU and Passekov VP (1990) Fundamentals of Mathematical Evolutionary Genetics. Dodrecht: Kluwer Academic Publishers. | |
