Human Population Genetics: Drift and Migration

Genetic drift is the effect of changes in genetic composition of a finite population, due to random replacement of alleles from one generation to the next. Migration effect specifies alterations caused by exchange of genes between populations.

Keywords: random genetic drift; gene flow; fixation index; effective population size; gene diversity; founder effect; human genome diversity

 References
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 Further Reading
    book Cavalli-Sforza LL and Bodmer WF (1971) The Genetics of Human Populations. San Francisco: Freeman.
    book Crow JF and Kimura M (1970) An Introduction to Population Genetics Theory. New York: Harper and Row.
    Handley LJ, Manica A, Goudet J and Balloux F (2007) Going the distance: human population genetics in a clinal world. Trends in Genetics 23: 432–439.
    Liu H, Prugnolle F, Manica A and Balloux F (2006) A geographically explicit genetic model of worldwide human-settlement history. American Journal of Human Genetics 79: 230–237.
    book Nei M (1987) Molecular Evolutionary Genetics. New York: Columbia University Press.
    Ramachandran S, Deshpande O, Roseman CC et al. (2005) Support from the relationship of genetic and geographic distance in human populations for a serial founder effect originating in Africa. Proceedings of the National Academy of Sciences of the USA 102: 15942–15947.
    Reed FA and Tishkoff SA (2006) African human diversity, origins and migrations. Current Opinion in Genetics & Development 16: 597–605.
    Sokal RR (1991) Ancient movement patterns determine modern genetic variances in Europe. Human Biology 63: 589–606.
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Chakraborty, Ranajit(Jul 2008) Human Population Genetics: Drift and Migration. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1002/9780470015902.a0001786.pub2]