Genome Evolution: Overview


The genome is the total genetic constitution of an organism. Understanding of the structure and evolution of genomes is undergoing a revolution with ability to sequence entire genomes. A key feature in the evolution of genomes is the creation of new genes, usually by duplication.

Keywords: Archaea; repetitive DNA; concerted evolution; selfish DNA; junk DNA

Further Reading

Cavalier‐Smith T (ed.) (1985) The Evolution of Genome Size. New York: Wiley.

Clayton RA, White O, Ketchum KA and Venter JC (1997) The first genome from the third domain of life. Nature 387: 459–460.

Douglas SE (1998) Plastid evolution: origins, diversity, trends. Current Opinion in Genetics and Development 8: 655–661.

Forterre P (1997) Archaea: what can we learn from their sequences? Current Opinion in Genetics and Development 7: 764–770.

Gilson PR, Maier U‐G and McFadden GI (1997) Size isn't everything, lessons in genetic miniaturization from nucleomorphs. Current Opinion in Genetics and Development 7: 800–806.

Gruar D and Li W‐H (1999) Fundamental of Molecular Evolution, 2nd edn. Sunderland, MA: Sinauer Associates.

Keeling PJ (1998) A kingdom's progress: archezona and the origin of eukaryotes. BioEssays 20: 87–95.

Koonin EV and Galperin MY (1997) Prokaryotic genomes: the emerging paradigm of genome‐based microbiology. Current Opinion in Genetics and Development 7: 757–763.

Li W‐H (1997) Molecular Evolution. Sunderland, MA: Sinauer Associates.

Logsdon JM Jr (1998) The recent origins of spliceosomal introns revisited. Current Opinion in Genetics and Development 8: 637–648.

Mushegia AR and Koonin EV (1996) A minimal gene set for cellular life derived by comparisons of complete bacterial genomes. Proceedings of the National Academy of Sciences of the USA 93: 10268–10273.

Olsen GJ and Woese CR (1997) Archaeal genomics. An overview. Cell 89: 991–994. [Four additional reviews covering different aspects of Archaeal genomics follow this overview.]

Page RDM and Holmes EC (1998) Molecular Evolution: A Phylogenetic Approach. Oxford: Blackwell Science.

Palmer JD (1997) The mitochondrion that time forgot. Nature 387: 454–455.

Sidow A (1996) Gen(om)e duplications in the evolution of early vertebrates. Current Opinion in Genetics and Development 6: 715–722.

Skrabanek L and Wolfe KH (1998) Eukaryote genome duplication – where's the evidence? Current Opinion in Genetics and Development 8: 694–700.

Singer M and Berg P (1991) Genes and Genomes. Herndon, VA: University Science Books.

Smit AFA (1996) The origin of interspersed repeats in the human genome. Current Opinion in Genetics and Development 6: 743–748.

TIGR (2000) TIGR – The Institute for Genomic Research. [] [The Institute for Genomic Research website provides a listing of all fully sequenced genomes.]

OGMP (2000) OGMP – The Organelle Genome Megasequencing Program [] [The Organelle Genome Megasequencing Program website provides a listing of fully sequenced mitochondrial and chloroplast genomes.]

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How to Cite close
Walsh, J Bruce(Apr 2001) Genome Evolution: Overview. In: eLS. John Wiley & Sons Ltd, Chichester. [doi: 10.1038/npg.els.0001810]