J Bruce Walsh, University of Arizona, Tucson, Arizona, USA
Published online: April 2001
DOI: 10.1038/npg.els.0001810
The genome is the total genetic constitution of an organism. Understanding of the structure and evolution of genomes is undergoing a revolution with ability to sequence entire genomes. A key feature in the evolution of genomes is the creation of new genes, usually by duplication.
Keywords: Archaea; repetitive DNA; concerted evolution; selfish DNA; junk DNA
| Further Reading | |
| book Cavalier-Smith T (ed.) (1985) The Evolution of Genome Size. New York: Wiley. | |
| Clayton RA, White O, Ketchum KA and Venter JC (1997) The first genome from the third domain of life. Nature 387: 459–460. | |
| Douglas SE (1998) Plastid evolution: origins, diversity, trends. Current Opinion in Genetics and Development 8: 655–661. | |
| Forterre P (1997) Archaea: what can we learn from their sequences? Current Opinion in Genetics and Development 7: 764–770. | |
| Gilson PR, Maier U-G and McFadden GI (1997) Size isn't everything, lessons in genetic miniaturization from nucleomorphs. Current Opinion in Genetics and Development 7: 800–806. | |
| book Gruar D and Li W-H (1999) Fundamental of Molecular Evolution, 2nd edn. Sunderland, MA: Sinauer Associates. | |
| Keeling PJ (1998) A kingdom's progress: archezona and the origin of eukaryotes. BioEssays 20: 87–95. | |
| Koonin EV and Galperin MY (1997) Prokaryotic genomes: the emerging paradigm of genome-based microbiology. Current Opinion in Genetics and Development 7: 757–763. | |
| book Li W-H (1997) Molecular Evolution. Sunderland, MA: Sinauer Associates. | |
| Logsdon JM Jr (1998) The recent origins of spliceosomal introns revisited. Current Opinion in Genetics and Development 8: 637–648. | |
| Mushegia AR and Koonin EV (1996) A minimal gene set for cellular life derived by comparisons of complete bacterial genomes. Proceedings of the National Academy of Sciences of the USA 93: 10268–10273. | |
| Olsen GJ and Woese CR (1997) Archaeal genomics. An overview. Cell 89: 991–994. [Four additional reviews covering different aspects of Archaeal genomics follow this overview.] | |
| book Page RDM and Holmes EC (1998) Molecular Evolution: A Phylogenetic Approach. Oxford: Blackwell Science. | |
| Palmer JD (1997) The mitochondrion that time forgot. Nature 387: 454–455. | |
| Sidow A (1996) Gen(om)e duplications in the evolution of early vertebrates. Current Opinion in Genetics and Development 6: 715–722. | |
| Skrabanek L and Wolfe KH (1998) Eukaryote genome duplication – where's the evidence? Current Opinion in Genetics and Development 8: 694–700. | |
| book Singer M and Berg P (1991) Genes and Genomes. Herndon, VA: University Science Books. | |
| Smit AFA (1996) The origin of interspersed repeats in the human genome. Current Opinion in Genetics and Development 6: 743–748. | |
| ePath TIGR (2000) TIGR – The Institute for Genomic Research. [http://www.tigr.org/tdb/index.shtml] [The Institute for Genomic Research website provides a listing of all fully sequenced genomes.] | |
| ePath OGMP (2000) OGMP – The Organelle Genome Megasequencing Program [http://megasun.bch.umontreal.ca/ogmpproj.html] [The Organelle Genome Megasequencing Program website provides a listing of fully sequenced mitochondrial and chloroplast genomes.] | |
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