Antimicrobials: Susceptibility Testing

Abstract

The ability of bacteria to resist the damaging effects of antimicrobials may be a normal characteristic of a particular species or may be acquired by a variety of genetic changes. Testing of bacteria to determine whether or not resistance is present is called susceptibility testing because the most frequent reasons for carrying out such tests is to monitor antibiotics to confirm that they are suitable for treatment of bacteria isolated from individual patients.

Keywords: antimicrobials; susceptibility testing; antibiotic resistance; inhibitory concentrations of antibiotics

Further Reading

Livermore DM (1995) β‐Lactamases in laboratory and clinical resistance. Clinical Microbiology, Reviews 8: 557–584.

Lorian V (ed.) (1996) Antibiotics in Laboratory Medicine, 4th edn. Baltimore: Williams and Wilkins.

National Committee for Clinical Laboratory Standards (1993) Performance Standards for Antimicrobial Susceptibility Testing Approved Standard, 4th edn. Document M2‐A4. Villanova, PA: NCCLS.

Weidemann B (1998) Evaluation of data from susceptibility testing. International Journal of Antimicrobial Agents 10: 218–219.

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How to Cite close
Williams, John D(Apr 2001) Antimicrobials: Susceptibility Testing. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0001994]