Antimicrobial Resistance: Epidemiology

Abstract

Antimicrobial resistance advances as epidemics of emerged resistance genes variably linked within a variety of genetic elements that spread through interconnecting bacterial populations of antimicrobial‐exposed people, animals and places.

Keywords: antimicrobial; resistance; selection; bacterial populations; plasmids

Further Reading

Donskey CJ, Chowdhry TK, Hecker MT et al. (2000) Effect of antibiotic therapy on the density of vancomycin‐resistant enterococci in the stool of colonized patients. New England Journal of Medicine 343(26): 1925–1932.

Hall R and Collis C (1995) Mobile gene casettes and integrons, capture and spread of genes by site‐specific recombination. Molecular Microbiology 15: 593–600.

Hughes VM and Datta N (1983) Conjugative plasmids in bacteria of the ‘pre‐antibiotic’ era. Nature 302(5910): 725–726.

Leclercq R and Courvalin P (1997) Resistance to glycopeptides in enterococci. Clinical Infectious Diseases 24(4): 545–554; quiz 555–556.

Medeiros AA (1997) Evolution and dissemination of beta‐lactamases accelerated by generations of beta‐lactam antibiotics. Clinical Infectious Diseases 24(Supplement 1): S19–45.

O’Brien TF, Pla MP, Mayer KH et al. (1985) Intercontinental spread of a new antibiotic resistance gene on an epidemic plasmid. Science 230(4721): 87–88.

Skurray RA and Firth N (1997) Molecular Evolution of Multiply‐antibiotic‐resistant Staphylococci. Chichester, UK: Wiley.

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How to Cite close
O’Brien, Thomas F(Jan 2003) Antimicrobial Resistance: Epidemiology. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0002002]