Vitamin E Deficiency

Abstract

Vitamin E is essential for the integrity of cellular membranes and deficiency of it results in membrane lipid peroxidation, dysfunction and cell death. Nutritional vitamin E deficiency is rare in humans, but rare genetic defects lead to tissue deficiency despite normal intestinal absorption.

Keywords: vitamin E; deficiency; neuropathy; fat malabsorption; tocopherol transport protein

References

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Further Reading

Arita M, Sato Y, Miyato A et al. (1995) Human alpha‐tocopherol transfer protein: cDNA cloning, expression and chromosomal localization. Journal of Biochemistry 306: 437–443.

Fernandez‐Zamorano A, Arnalich F, Codoceo R et al. (1988) Hemolytic anaemia and susceptibility to hydrogen‐peroxide hemolysis in children with vitamin E‐deficiency and chronic liver disease. Journal of Medicine 18: 317–334.

Kaempf DE and Linderkamp O (1998) Do healthy premature infants fed breast milk need vitamin E supplementation: alpha‐ and gamma‐tocopherol levels in blood components and buccal mucosal cells. Pediatrics Research 44: 54–59.

Meydani SN and Hayek M (1992) Vitamin E and immune response. Chandra RK Proceedings of International Conference on Nutrition and Immunity, pp. 105–128. St John's, Newfoundland: ARTS Biomedical Publishers and Distributors

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How to Cite close
Meydani, Mohsen, Koga, Takuro, and Ali, Samina(Jan 2003) Vitamin E Deficiency. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0002109]