Ischaemic Heart Disease


The clinical spectrum of ischaemic heart disease encompasses a variety of acute and chronic conditions including silent ischaemia, chronic stable angina, myocardial infarction, ischaemic cardiomyopathy and sudden cardiac death. Its pathogenesis and treatment is the subject of much ongoing research and debate.

Keywords: atherosclerosis; myocardial infarction; congestive heart failure; coronary artery disease; thrombolysis

Figure 1.

Changes in mortality rates for coronary heart disease (CHD), stroke, and noncardiovascular disease (CVD) in the USA since 1950, age‐adjusted to the 2000 standard. aComparability ratio applied to rates for the years 1968–1978. bTotal mortality minus CVD (excluding congenital). From National Institute of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI) Morbidity and Mortality (1998) Chartbook on Cardiovascular, Lung, and Blood Diseases.

Figure 2.

Drawing of a nonobstructive atheromatous plaque in a coronary artery.



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Further Reading

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Lewis, David, Wang, Qing, and Topol, Eric(Apr 2001) Ischaemic Heart Disease. In: eLS. John Wiley & Sons Ltd, Chichester. [doi: 10.1038/npg.els.0002113]