Pain: Control

Abstract

Pain is an unpleasant sensation coupled with individualized unpleasant emotions. It is easier to treat acute pain than chronic pain because chronic pain can lead to maladaptive behaviour. Chronic pain is best controlled with multidisciplinary pain management.

Keywords: acute pain; chronic pain; pain pathways; nociceptors; neurotransmitters; neuropathic pain; pain management; analgesic agents

Figure 1.

Second‐order neurons. DRG, dorsal root ganglion. Courtesy of William G Bose, reproduced by permission.

Figure 2.

Excitatory neurotransmitters inhibit the firing of second‐order neurons. Courtesy of William G Bose, reproduced by permission.

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References

American Academy of Pain Medicine and American Pain Society (1997) Consensus Statement: The Use of Opioids for the Treatment of Chronic Pain, pp. 1–4. Glenview, IL: American Academy of Pain Medicine.

Basbaum AI (1996) Memories of pain. Science and Medicine 3: 22–31.

Berde CB (1997) New and old anticonvulsants for the management of pain. IASP News Jan/Feb: 3–5.

Bonica JJ (ed.) (1990) Definitions and taxonomy of pain. In: The Management of Pain, vol. 2, pp. 18–27. Philadelphia: Lea and Febiger

Chabal C, Jacobsen L, Mariono A, Chaney E and Britell CW (1992) The use of oral mexiletine for the treatment of pain after peripheral nerve injury. Anesthesiology 76: 513–517.

Eisenach JC, DuPen S, Dubois M, Miguel R and Allin D (1995) The Epidural Clonidine Study Group. Epidural clonidine analgesia for intractable cancer pain. Pain 61: 391–399.

Laine L, Hawkey C, Harper S et al. (1999) Effect of the COX‐2 specific inhibitor (C‐2SI) rofecoxib on ulcer formation: a double blind comparison with ibuprofen and placebo. Gastroenterology 116 (4 pt. 2): G0996.

Malmberg AB and Yaksh TL (1994) Voltage‐sensitive calcium channels in spinal nociceptive processing: blockade of N‐ and P‐type channels inhibits formalin induced nociception. Journal of Neuroscience 18: 4882–4890.

Medical Board of California (1994) Prescribing Controlled Substances for Pain. Medical Board of California Act. Rep., pp. 4–5. Sacramento, CA: Medical Board of California.

Merskey H, Lindblom U (1994) Pain terms. In: Merskey H and Bogduk N (eds) Classification of Chronic Pain, pp. 207–213. Seattle: IASP Press.

Song S‐O and Carr DB (1999) Pain and memory. In: Pain: Clinical Updates, vol. VII(1). Seattle: IASP Press.

Treede RD, Kenshelo DR, Gracely RH and Jones AK (1999) Cortical representation of pain. Pain 79: 105–111.

World Health Organization (1990) Cancer Pain Relief and Palliative Care. Geneva: WHO.

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How to Cite close
Russo, Cathy M(Apr 2001) Pain: Control. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0002205]