References
Anisimova M and
Liberles DA
(2007)
The quest for natural selection in the age of comparative genomics.
Heredity
99:
567–579.
Boyko AR,
Quignon P,
Li L et al.
(2010)
A simple genetic architecture underlies morphological variation in dogs.
PLoS Biology
8:
e1000451.
Buckler ES,
Holland JB,
Bradbury PJ et al.
(2009)
The genetic architecture of maize flowering time.
Science
325:
714–718.
Carbone MA,
Jordan KW,
Lyman RF et al.
(2006)
Phenotypic variation and natural selection at Catsup, a pleiotropic quantitative trait gene in Drosophila.
Current Biology
16:
912–919.
Chapuis E,
Martin G and
Goudet J
(2008)
Effects of selection and drift on G matrix evolution in a heterogeneous environment: a multivariate Qst‐Fst Test with the freshwater snail Galba truncatula.
Genetics
180:
2151–2161.
Chun YJ,
Nason JD and
Moloney KA
(2009)
Comparison of quantitative and molecular genetic variation of native vs. invasive populations of purple loosestrife (Lythrum salicaria L., Lythraceae).
Molecular Ecology
18:
3020–3035.
Cook RK,
Christensen SJ,
Deal JA et al.
(2012)
The generation of chromosomal deletions to provide extensive coverage and subdivision of the Drosophila melanogaster genome.
Genome Biology
13:
R21.
Crow JF
(2007)
Haldane, Bailey, Taylor and recombinant‐inbred lines.
Genetics
176:
729–732.
Davis RH
(2004)
The age of model organisms.
Nature Reviews Genetics
5(1):
69–76.
Ehrenreich IM,
Bloom J,
Torabi N et al.
(2012)
Genetic architecture of highly complex chemical resistance traits across four yeast strains.
PLoS Genetics
8:
e1002570.
Ehrenreich IM,
Torabi N,
Jia Y et al.
(2010)
Dissection of genetically complex traits with extremely large pools of yeast segregants.
Nature
464:
1039–1042.
Falconer DS and
Mackay TF
(1996)
Introduction to Quantitative Genetics.
Essex: Addison Wesley Longman.
Fanara JJ,
Robinson KO,
Rollmann SM,
Anholt RR and
Mackay TF
(2002)
Vanaso is a candidate quantitative trait gene for Drosophila olfactory behavior.
Genetics
162:
1321–1328.
Frankel N,
Erezyilmaz DF,
McGregor AP et al.
(2011)
Morphological evolution caused by many subtle‐effect substitutions in regulatory DNA.
Nature
474:
598–603.
Fisher RA
(1930)
The Genetical Theory of Natural Selection.
Oxford: Oxford University Press.
Gerke J,
Lorenz K and
Cohen B
(2009)
Genetic interactions between transcription factors cause natural variation in yeast.
Science
323:
498–501.
Gibson G
(2010)
Hints of hidden heritability in GWAS.
Nature Genetics
42:
558–560.
Gibson G
(2011)
Rare and common variants: twenty arguments.
Nature Reviews Genetics
13:
135–145.
Goldschmidt R
(1940)
The Material Basis of Evolution.
New Haven: Yale University Press.
Hill WG
(2012)
Quantitative genetics in the genomics era.
Current Genomics
13:
196–206.
Hill WG,
Goddard ME and
Visscher PM
(2008)
Data and theory point to mainly additive genetic variance for complex traits.
PLoS Genetics
4:
e1000008.
Huang W,
Richards S,
Carbone MA et al.
(2012)
Epistasis dominates the genetic architecture of Drosophila quantitative traits.
Proceedings of the National Academy of Sciences of the USA
109:
15553–15559.
Kimura M
(1983)
The Neutral Theory of Molecular Evolution.
Cambridge: Cambridge University Press.
Lande R
(1992)
Neutral theory of quantitative genetic variance in an island model with local extinction and recolonization.
Evolution
46:
381–389.
Lande R and
Arnold SJ
(1983)
The measurement of selection on correlated characters.
Evolution
37:
1210–1226.
Leinonen T,
O'Hara RB,
Cano JM et al.
(2008)
Comparative studies of quantitative trait and neutral marker divergence: a meta‐analysis.
Journal of Evolutionary Biology
21:
1–17.
Li Y,
Huang Y,
Bergelson J,
Nordborg M and
Borevitz JO
(2010)
Association mapping of local climate‐sensitive quantitative trait loci in Arabidopsis thaliana.
Proceedings of the National Academy of Sciences of the USA
107:
21199–21204.
Lorenz K and
Cohen BA
(2012)
Small‐ and large‐effect quantitative trait locus interactions underlie variation in yeast sporulation efficiency.
Genetics
192:
1123–1132.
Lynch M and
Walsh JB
(1998)
Genetics and Analysis of Quantitative Traits.
Sunderland: Sinauer Associates.
Mackay TF
(2001)
The genetic architecture of quantitative traits.
Annual Reviews of Genetics
35:
303–339.
Mackay TF,
Richards S,
Stone EA et al.
(2012)
The Drosophila melanogaster genetic reference panel.
Nature
482:
173–178.
McKay JK and
Latta RG
(2002)
Adaptive population divergence: markers, QTL and traits.
Trends in Ecology and Evolution
17:
285–291.
Merilä J and
Bjorklund M
(2004)
Phenotypic integration as a constraint and adaptation. In:
Pigliucci M and
Preston K (eds)
The Evolutionary Biology of Complex Phenotypes, pp.
107–129.
Oxford: Oxford University Press.
Merilä J and
Crnokrak P
(2001)
Comparison of genetic differentiation at marker loci and quantitative traits.
Journal of Evolutionary Biology
14:
892–903.
Orr HA
(2005)
The genetic theory of adaptation: a brief history.
Nature Reviews Genetics
6:
119–127.
Pelgas B,
Bousquet J,
Meirmans PG,
Ritland K and
Isabel N
(2011)
QTL mapping in white spruce: gene maps and genomic regions underlying adaptive traits across pedigrees, years and environments.
BMC Genomics
12:
145.
Richter‐Boix A,
Teplitsky C,
Rogell B and
Laurila A
(2010)
Local selection modifies phenotypic divergence among Rana temporaria populations in the presence of gene flow.
Molecular Ecology
19:
716–731.
Rockman MV
(2012)
The QTN program and the alleles that matter for evolution: all that's gold does not glitter.
Evolution
66:
1–17.
Rogell B,
Eklund M,
Thörngren H,
Laurila A and
Höglund J
(2010)
The effects of selection, drift and genetic variation on life‐history trait divergence among insular populations natterjack toad, Bufo calamita.
Molecular Ecology
19:
2229–2240.
Rogers SM,
Tamkee P,
Summers B et al.
(2012)
Genetic signature of adaptive peak shift in threespine stickleback.
Evolution
66:
2439–2450.
Santure AW,
Ewen JG,
Sicard D,
Roff DA and
Møller AP
(2010)
Population structure in the barn swallow, Hirundo rustica: a comparison between neutral DNA markers and quantitative traits.
Biological Journal of the Linnean Society
99:
306–314.
Schluter D
(1996)
Adaptive radiation along genetic lines of least resistance.
Evolution
50:
1766–1774.
Stapley J,
Reger J,
Feulner PG et al.
(2010)
Adaptation genomics: the next generation.
Trends in Ecology and Evolution
25:
705–712.
Tian F,
Bradbury PJ,
Brown PJ et al.
(2011)
Genome‐wide association study of leaf architecture in the maize nested association mapping population.
Nature Genetics
43:
159–162.
Visscher PM,
Brown MA,
McCarthy MI and
Yang J
(2012)
Five years of GWAS discovery.
American Journal of Human Genetics
90:
7–24.
Volis S and
Zhang YH
(2010)
Separating effects of gene flow and natural selection along an environmental gradient.
Evolutionary Biology
37:
187–199.
Whitlock MC
(2008)
Evolutionary inference from QST.
Molecular Ecology
17:
1885–1896.
Wright S
(1931)
Evolution in Mendelian populations.
Genetics
16:
97–159.
Wright S
(1978)
Evolution and the Genetics of Populations, Volume 4: Variabililty Within and Among Populations.
London: The University of Chicago Press.
Zhen Y and
Andolfatto P
(2012)
Methods to detect selection on noncoding DNA.
Methods in Molecular Biology
856:
141–159.
Further Reading
Flint J and
Mackay TF
(2009)
Genetic architecture of quantitative traits in mice, flies, and humans.
Genome Research
19(5):
723–733.
Orr HA
(2005)
Theories of adaptation: what they do and don't say.
Genetica
123:
3–13.
Pavlidis P,
Metzler D and
Stephan W
(2012)
Selective sweeps in multilocus models of quantitative traits.
Genetics
192:
225–239.
Slate J
(2005)
Quantitative trait locus mapping in natural populations: progress, caveats and future directions.
Molecular Ecology
14:
363–379.