Osteoarthritis

Abstract

Osteoarthritis is a pathological condition of articular cartilage and its underlying bone associated with biomechanical abnormalities and secondary inflammation. These changes result in cartilage loss, subchondral sclerosis, cyst and osteophyte formation, and the clinical sequelae of pain, swelling, deformity and loss of motion in affected joints.

Keywords: ageing; articular cartilage; cartilage transplantation; osteoarthritis; total joint replacement

Further Reading

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How to Cite close
Chu, Constance R, and Thornhill, Thomas S(Apr 2001) Osteoarthritis. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0002309]