Brown‐Séquard, Charles Edouard


1817–1894 Mauritian‐born British (later French) physiologist who defined the sensory pathways in the spinal cord, emphasized the importance of functional processes in the operation of the nervous system, showed experimentally that the adrenal glands are essential to life, and founded modern hormone replacement therapy by his use of organ extracts.

Keywords: sensory pathways; excitation; inhibition; hormones; organ extracts

Further Reading

Brown‐Séquard CE (1860) Course of Lectures on the Physiology and Pathology of the Central Nervous System. Philadelphia: Collins.

Brown‐Séquard CE (1878) Notice sur les travaux scientifiques de M.C.E. Brown‐Séquard. Paris: Masson.

Brown‐Séquard CE (1889) Note on the effects produced on man by subcutaneous injections of a liquid obtained from the testicles of animals. Lancet ii: 105–107.

Aminoff MJ (1993) Brown‐Séquard: A Visionary of Science. New York: Raven Press.

Berthelot M (1898) Notice sur la vie et les travaux de M. Brown‐Séquard. Paris: Institut de France.

Olmsted JMD (1946) Charles Edouard Brown‐Séquard. A Nineteenth Century Neurologist and Endocrinologist. Baltimore: Johns Hopkins Press.

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How to Cite close
Aminoff, MJ(May 2001) Brown‐Séquard, Charles Edouard. In: eLS. John Wiley & Sons Ltd, Chichester. [doi: 10.1038/npg.els.0002375]