EM Tansey, Wellcome Institute for the History of Medicine, London, UK
Published online: April 2001
DOI: 10.1038/npg.els.0002396
1875–1968 English physiologist and pharmacologist, whose work on chemical neurotransmission, especially by acetylcholine, elucidated a basic mechanism of nerve function.
Keywords: chemical neurotransmission; acetylcholine; biological standards; histamine
| Further Reading | |
| Dale HH (1933) Progress in autopharmacology: a survey of present knowledge of the chemical regulation of certain functions by natural constituents of tissues. 1. Introduction, the action of histamine and the evidence restricting its probable significance. Evidence for other natural vasodilators. 2. Acetylcholine: its natural occurrence and probable function. Adenosine and its derivatives. 3. Kallikrein. Vasodilators from blood vessels, blood, intestine and brain. General survey of the possible functions of such constituents of the tissues, in relation to those of nerves and specific hormones. Johns Hopkins Hospital Bulletin 53: 297–312; 312–329; 329–347. | |
| Dale HH (1938) William Henry Welch Lectures: Acetylcholine as a chemical transmitter of the effects of nerve impulses. 1. History of ideas and evidence. Peripheral autonomic actions. Functional nomenclature of nerve fibres. 2. Chemical transmission at ganglionic synapses and voluntary motor nerve endings. Some general considerations. Journal of Mount Sinai Hospital 4: 401–414; 416–429. | |
| Dale HH (1950) The pharmacology of histamine; with a brief survey of evidence for its occurrence, liberation and participation in natural reactions. Annals of the New York Academy of Sciences 50: 1017–1028. | |
| book Dale HH (1953) Adventures in Physiology. London: Pergamon Press. | |
| Dale HH (1958) Autobiographical sketch. Perspectives in Biology and Medicine 1: 125–137. | |
| Feldberg WS (1970) Henry Hallett Dale 1875–1968. Biographical Memoirs of Fellows of the Royal Society of London 16: 77–174. | |
| book Feldberg WS (1979) "The early history of synaptic and neuromuscular transmission by acetylcholine: reminiscences of an eye witness". The Pursuit of Nature: Informal Essays on the History of Physiology, pp. 65–83 Cambridge: Cambridge University Press. | |
| book Tansey EM (1990) "Sir Henry Hallett Dale". In: Fox DM, Meldrum M and Rezak I (eds) Nobel Laureates in Medicine or Physiology: A Biographical Dictionary, pp. 115–118. New York: Garland | |
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