In 1819, he started his medical studies at the University of Bonn in Germany. In 1826, he formulated the Law of Specific Sense Energy. With his anatomical and physiological research he became one of the most important scientists of life sciences in Europe. Since 1833 until his death, he was director of the Institute of Anatomy and Physiology at the University of Berlin. He mainly worked in the field of sensory, haematological, pathological anatomy and physiology as well as systematic zoology and marine biology. Müller's exceptional position in the history of medicine and zoology was not only connected with his own research, but was also due to his epistemological reflections on scientific physiology and experimental medicine and his role as an influential and important teacher.