Phagosomes: Methods for Preparation

Abstract

Phagosomes are dynamic cellular compartments in which cells kill and degrade intracellular pathogens. Although phagosomes normally mature into phagolysosomes to perform their tasks, several pathogens have developed ways to alter this maturation process in order to survive and replicate within their host cells. Isolation of pure phagosomes will allow the analysis of their composition and function in health and their modifications during infectious diseases.

Keywords: phagocytosis; cell fractionation; organelle; microorganism; phagolysosome

References

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Desjardins, Michel(Apr 2001) Phagosomes: Methods for Preparation. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0002593]