Transgenic Mice Production

Jon W Gordon, Mount Sinai Medical Center, New York, New York, USA

Published online: April 2001

DOI: 10.1038/npg.els.0002667

Transgenic mice are those into which foreign genetic material has been inserted.

Keywords: microinjection; genetic engineering; transgenesis

 References
    Gordon JW and Ruddle FH (1981) Integration and stable germ line transmission of genes injected into mouse pronuclei. Science 214: 1244–1246.
    proceedings Gordon JW, Scangos GA, Plotkin DJ, Barbosa JA, and Ruddle FH (1980) Genetic transformation of mouse embryos by microinjection of purified DNA. Proceedings of the National Academy of Sciences of the USA 77: 7380–7384.
 Further Reading
    Gordon JW (1989) Transgenic animals. International Review of Cytology 115: 171–230.

Related Sub-Topics:

Model Organisms and Human Disease | Techniques and Tools in Clinical Genetics | Chromosomes and Chromatin Modifications | Techniques and Tools in Molecular Biology
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Article Title: Transgenic Mice Production
 
How to Cite close
Gordon, Jon W(Apr 2001) Transgenic Mice Production. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0002667]