Black, James Whyte

Viviane Quirke, The Royal Institution of Great Britain, London, UK

Published online: April 2001

DOI: 10.1038/npg.els.0002739

1924– British pharmacologist who developed the beta blocker propranolol and the anti-ulcer drug cimetidine.

Keywords: rational drug design; medicine; angina pectoris; peptic ulcers; histamine; adrenaline; beta adrenoceptor; beta blocker; propranolol; inderal; hypertension; cimetidine; tagamet

 Further Reading
    Black JW and Stephenson JS (1962) Pharmacology of a new adrenergic beta-receptor blocking compound (nethalide). Lancet ii: 311–314.
    Black JW, Duncan WA, Durant CJ, Ganellin CR and Parsons EM (1972) Definition and antagonism of histamine H2-receptors. Nature 236: 385–390.
    book Williams T (ed.) (1994) Biographical Dictionary of Scientists, p. 55. Glasgow: Harper Collins.
    book George KH (1995) "James Black, 1924–: English pharmacologist". In: Murray EJ (ed.) Notable Twentieth-century Scientists, vol. 1. pp. 185–187. New York: Gale.
    Gerskowitch WP, Hull RAD and Shankley NP (1988) The ‘pharmaceutical toolmaker's rational approach to drug design: an appreciation of Sir James Black. Trends in Pharmacological Sciences 9: 435–437.

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Quirke, Viviane(Apr 2001) Black, James Whyte. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0002739]