Duve, Christian Rene De


Born in 1917, Belgian cytologist and biochemist who in 1974 was awarded the Nobel Prize for Physiology or Medicine for his discoveries of the cellular organelles, the lysosome and the peroxisome. Since the 1980s, De Duve contributed to the theoretical understanding of the origin and evolution of life.

Keywords: cell fractionation; cellular organelles; Claude Albert; constraints on natural selection; digestive enzymes; lysosomes; origin of life; Palade George; peroxisomes; protometabolism

Further Reading

Bainton DF (1981) The discovery of lysosomes. Journal of Cell Biology 91(3, part 2): 66–76.

De Duve C (1974) Exploring cells with a centrifuge (Nobel Lecture). In: Lindsten J (ed.) (1992) Nobel Lectures, Physiology or Medicine 1971–1980, pp. 152–170 Singapore: World Scientific Publishing Co. [http://nobelprize.org/nobel_prizes/medicine/laureates/1974/duve‐lecture.pdf].

De Duve C (1974) [with Addendum, December 1997] Autobiography. In: Odelberg W (ed.) (1975) Les Prix Nobel en 1974 Stockholm: Nobel Foundation. [http://nobelprize.org/nobel_prizes/medicine/laureates/1974/duve‐autobio.html].

De Duve C (2005) Singularities: Landmarks on the Pathways of Life. Cambridge: Cambridge University Press.

De Duve C and Beaufay H (1981) A short history of tissue fractionation. Journal of Cell Biology 91(3, part 2): 293–299.

Fry I (2000) The Emergence of Life on Earth. New Brunswick, NJ: Rutgers University Press.

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How to Cite close
Fry, Iris(Sep 2010) Duve, Christian Rene De. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1002/9780470015902.a0002764]