McCarty, Maclyn

1911– American medical microbiologist whose work on the transforming principle of the pneumonia-causing bacteria led to the discovery that DNA was the chemical basis of genetic information.

Keywords: DNA; pneumococcus; bacterial transformation; transforming principle; deoxyribonuclease (DNAase)

 Further Reading
    Avery OT, MacLeod CM and McCarty M (1944) Studies on the nature of the substance inducing transformation of pneumococcal types. I. Induction of transformation by a desoxyribonucleic acid fraction isolated from pneumococcus type III. Journal of Experimental Medicine 79: 137–158.
    McCarty M and Avery OT (1946) Studies on the nature of the substance inducing transformation of pneumococcal types. II. Effect of desoxyribonuclease on the biological activity of the transforming substance. Journal of Experimental Medicine 83: 89–96.
    book McCarty M (1985) The Transforming Principle. Discovering that Genes are made of DNA. New York: WW Norton.
Contact Editor close
Submit a note to the editor about this article by filling in the form below.

* Required Field

How to Cite close
Sankaran, Neeraja(Apr 2001) McCarty, Maclyn. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0002872]