1927–2002 Argentinian molecular biologist who, with Georges Köhler, perfected the technique of monoclonal antibody production from hybridomas.
Keywords: hybridoma technique; monoclonal antibody
Milstein, Cesar
JM Cruse, University of Mississippi Medical Center, Jackson, Mississippi, USA
RE Lewis, University of Mississippi Medical Center, Jackson, Mississippi, USA
Published online: July 2002
DOI: 10.1038/npg.els.0002877
| Further Reading | |
| book Milstein C (1982) "Monoclonal antibodies from hybrid myelomas: theoretical aspects and some general comments". In: McMichael AJ and Febre JW (eds) Monoclonal Antibodies in Clinical Medicine, pp. 3–13. London: Academic Press. | |
| Milstein C (1986) From antibody structure to immunological diversification of immune response. Science 231: 1261–1268. | |
| Köhler GF and Milstein C (1975) Continuous cultures of fused cells secreting antibody of predefined specificity. Nature, London 256: 495–497. | |
| book Clark WR (1991) The Experimental Foundations of Modern Immunology. New York: John Wiley. | |
| book Goding JW (1986) Monoclonal Antibodies: Principles and Practice. Production and Application of Monoclonal Antibodies in Cell Biology, Biochemistry and Immunology, 2nd edn. London: Academic Press. | |
| book Hurrell JGR (eds) (1982) Monoclonal Hybridoma Antibodies: Techniques and Applications. Boca Raton, FL: CRC Press. | |
| book LeBlanc PA (1985) "Monoclonal antibodies: Novel to Nobel". In: Cruse JM and Lewis RE (eds) The Year in Immunology 1984–85, pp. 136–142. Basel: Karger. | |
| book McMichael AJ and Fabre JW (eds) (1982) Monoclonal Antibodies in Clinical Medicine. London: Academic Press. | |
| Wade N (1982) Hybridomas: The making of a revolution. Science 215: 1073–1075. | |
