Smith, Hamilton Othanel

JA Witkowski, Cold Spring Harbor Laboratory, New York, USA

Published online: April 2001

DOI: 10.1038/npg.els.0002913

1931– American scientist who elucidated the action of bacterial restriction enzymes that cut DNA molecules at specific places.

Keywords: DNA; restriction enzymes; gene mapping

 Further Reading
    Smith HO and Wilcox KW (1970) A restriction enzyme for Hemophilus influenzae. I Purification and general properties. Journal of Molecular Biology 51: 379–391.
    Kelly TJ Jr and Smith HO (1970) A restriction enzyme for Hemophilus influenzae. II Base sequence of the recognition site. Journal of Molecular Biology 51: 393–409.
    Smith HO (1979) Nucleotide sequence specificity of restriction endonucleases. Science 205: 455–462.
    Fleischmann RD, Adams MD, White O et al. (1995) Whole-genome random sequencing and assembly of Hemophilus influenzae Rd. Science 269: 496–512.

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Article Title: Smith, Hamilton Othanel
 
How to Cite close
Witkowski, JA(Apr 2001) Smith, Hamilton Othanel. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0002913]