Large Fermenters


A fermenter is a container in which a biological process can be carried out. Organisms, substrates and nutrients are brought together in the fermenter and maintained there in a favourable environment.

Keywords: bubble columns; heat generation; microcarrier; oxygen dissolution; suspended growth

Figure 1.

Stirred‐tank fermenter.

Figure 2.

Gas‐sparged fermenters: (a) air‐lift; (b) bubble‐column.


Further Reading

Winkler MA (1988) Application of the principles of fermentation engineering to biotechnology. In: Wiseman A (ed.) Principles of Biotechnology, 2nd edn, pp. 83–135. Guildford: Surrey University Press.

Winkler MA (1990) Problems in fermenter design and operation. In: Winkler MA (ed.) Chemical Engineering Problems in Biotechnology, pp. 215–350. Amsterdam: Elsevier/SCI.

Winkler MA (1995) Fermenter design and operation. In: Wiseman A (ed.) Handbook of Enzyme Biotechnology, part B, pp. 353–378. Upper Saddle River, NJ: Prentice‐Hall.

Winkler MA (1995) Fermentation process design. In: Wiseman A (ed.) Handbook of Enzyme Biotechnology part A, pp. 9–30. Upper Saddle River, NJ: Prentice‐Hall.

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How to Cite close
Winkler, Michael A(Apr 2001) Large Fermenters. In: eLS. John Wiley & Sons Ltd, Chichester. [doi: 10.1038/npg.els.0002970]