Abstract
Protein design is the engineering of natural amino acid sequences to modify and/or create desired protein structures or functions.
Keywords: protein; inverse folding; sequence sampling; automated design; molecular evolution
Protein Design
Emmanuel Lacroix, European Molecular Biology Laboratory, Heidelberg, Germany
Luis Serrano, European Molecular Biology Laboratory, Heidelberg, Germany
Published online: April 2001
DOI: 10.1038/npg.els.0003034
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Further Reading
DeGrado WF, Wasserman ZR and Lear JD (1989) Protein design, a minimalist approach. Science 243: 622–628.
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Lacroix E and Serrano L (2000) The EMBL Protein Design Unit. [http://ProteinDesign.EMBL-Heidelberg.DE]
Petrounia IP and Arnold FH (2000) Designed evolution of enzymatic properties. Current Opinion in Biotechnology 11: 325–330.
Street AG and Mayo SL (1999) Computational protein design. Structure with Folding and Design 7: R105–109.
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How to Cite
Lacroix, Emmanuel, and Serrano, Luis(Apr 2001) Protein Design. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0003034]
