History of Protein Chemistry


Protein chemistry may be defined as the study of the structure and chemical properties of proteins.

Keywords: proteins; polypeptides; amino acids; macromolecules

Further Reading

de Chadarevian S (1996) Sequences, conformation, information: biochemists and molecular biologists in the 1950s. Journal of the History of Biology 29: 361–386.

Fruton JS (1979) Early theories of protein structure. Annals of the New York Academy of Sciences 325: 1–18.

Fruton JS (1985) Contrasts in scientific style. Emil Fischer and Franz Hofmeister: their research groups and their theory of protein structure. Proceedings of the American Philosophical Society 129: 313–370.

Geison GL (1969) The protoplasmic theory of life and the vitalist–mechanist debate. Isis 60: 273–292.

Glas E (1983) Bio‐science between experiment and ideology, 1835–50. Studies in the History and Philosophy of Science 14: 39–57.

Judson HF (1979) The Eighth Day of Creation: Makers of the Revolution in Biology. New York: Simon and Schuster.

Olby RC (1985) The ‘mad pursuit’: X‐ray crystallographers’ search for the structure of haemoglobin. History and Philosophy of Life Science 7: 171–193.

Tanford C and Reynolds J (1999) Protein chemists bypass the colloid/macromolecule debate. Ambix 46: 33–51.

Teich M and Needham DM (1992) A Documentary History of Biochemistry. Rutherford, NJ: Fairleigh Dickinson Universities Press.

Vickery HB and Schmidt CLA (1931) The history of the discovery of the amino acids. Chemical Reviews 9: 169–318.

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Hunter, Graeme K(Feb 2002) History of Protein Chemistry. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0003464]