Cold‐shock Response in Microorganisms

Several species of bacteria are capable of mounting what is known as the cold-shock response. This is induced upon a sudden decrease in external temperature and results in the transiently enhanced synthesis of a set of proteins, termed cold-shock proteins, which allow the bacteria to adapt to low temperature.

Keywords: membrane fluidity; cold shock; RNA chaperone; Csp family

Figure 1. A schematic model of the cold-shock response pathway based on the ribosomes as the temperature sensors.
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 References
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    book Inouye M and Phadtare S (2007) "The cold-shock response". In: Glansdorff CGaN (ed.) Physiology and Biochemistry of Extremophiles, pp. 180–193. Washington, DC: ASM Press.
    Jiang W, Hou Y and Inouye M (1997) CspA, the major cold-shock protein of E. coli, is an RNA chaperone. Journal of Biological Chemistry 272: 196–202.
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    Kaneda T (1991) Iso- and anteiso-fatty acids in bacteria: biosynthesis, function, and taxonomic significance. Microbiology Reviews 55: 288–302.
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    Phadtare S (2004) Recent developments in bacterial cold-shock response. Current Issues in Molecular Biology 6: 125–136.
    Phadtare S, Alsina J and Inouye M (1999) Cold-shock response and cold-shock proteins. Current Opinion in Microbiology 2: 175–180.
    book Phadtare S and Inouye M (2007) "The cold shock proteins". In: Margesin R, Schinner F, Marx J-C and Gerday C (eds) Psychrophiles: From Biodiversity to Biotechnology. Heidelberg, Germany: Springer.
    book Phadtare S, Yamanaka K and Inouye M (2000) The Cold Shock Response in the Bacterial Stress Responses. Washington, DC: ASM Press.
    VanBogelen RA and Neidhardt FC (1990) Ribosomes as sensors of heat and cold shock in E. coli. Proceedings of the National Academy of Sciences of the USA 87: 5589–5593.
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 Further Reading
    Graumann PL and Marahiel MA (1998) A superfamily of proteins that contain the cold-shock domain. Trends in Biochemical Sciences 23: 286–290.
    Thieringer HA, Jones PG and Inouye M (1998) Cold shock and adaptation. BioEssays 20: 49–57.
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Schumann, Wolfgang, Inouye, Masayori, and Phadtare, Sangita(Sep 2008) Cold‐shock Response in Microorganisms. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1002/9780470015902.a0003560.pub2]