Cold‐shock Response in Microorganisms


Several species of bacteria are capable of mounting what is known as the cold‐shock response. This is induced upon a sudden decrease in external temperature and results in the transiently enhanced synthesis of a set of proteins, termed cold‐shock proteins, which allow the bacteria to adapt to low temperature.

Keywords: membrane fluidity; cold shock; RNA chaperone; Csp family

Figure 1.

A schematic model of the cold‐shock response pathway based on the ribosomes as the temperature sensors.



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Further Reading

Graumann PL and Marahiel MA (1998) A superfamily of proteins that contain the cold‐shock domain. Trends in Biochemical Sciences 23: 286–290.

Thieringer HA, Jones PG and Inouye M (1998) Cold shock and adaptation. BioEssays 20: 49–57.

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Schumann, Wolfgang, Inouye, Masayori, and Phadtare, Sangita(Sep 2008) Cold‐shock Response in Microorganisms. In: eLS. John Wiley & Sons Ltd, Chichester. [doi: 10.1002/9780470015902.a0003560.pub2]