History of Malaria


The history of malaria is concerned with the prehistory of malaria parasites, the clinical description of febrile illnesses associated with swamps and marshes and the identification of the four human malaria parasites and the mosquito vector. Through understanding of the life cycle methods of control (pre DDT) and treatment were developed and attempts made to achieve global eradication.

Keywords: plasmodia; anopheles; entomology; antimalarials; drug resistance

Further Reading

Bruce‐Chwatt LJ and Zulueta J de (1980) The Rise and Fall of Malaria in Europe: A Historico‐epidemiological Study. Oxford: Oxford University Press.

Bynum WF and Overy C (1998) The Beast in the Mosquito: The Correspondence of Ronald Ross & Patrick Manson. Amsterdam, The Netherlands: Rudopi.

Escalante AA and Ayala FJ (1996) Molecular paleogenetics: the evolutionary history of Plasmodium and related protists. In: Jablonski D, Erwin DH and Lipps JH (eds) Evolutionary Paleobiology, pp. 21–41. Chicago and London: University of Chicago Press.

Escalante AA, Lala AA and Ayala FJ (1998) Genetic polymorphism and natural selection in the malaria parasite Plasmodium falciparum. Genetics 149: 189–202.

Harrison G (1978) Mosquitoes, Malaria and Man: A History of Hostilities since 1880. New York: E P Dutton.

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Power, Helen Joy(Apr 2001) History of Malaria. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0003575]