History of Sulfonamides

Abstract

The sulfonamides were the first effective antibacterial drugs. As they were developed a decade before the general introduction of antibiotics, bacteria began to acquire resistance to them as a consequence of their overuse.

Keywords: chemistry; drugs and chemicals; drug therapy

Further Reading

Domagk GJ (1935) Ein Beitrag zur Chemotherapie der bakteriellen infektionen. Deutsche medizinische Wochenschrift 61: 250–253. In Brock TD (trans and ed) Milestones in Microbiology: 1556 to 1940, pp. 195–199. Washington, DC: ASM Press.

Sneader W (1996) Drug Prototypes and their Exploitation, pp. 589–620. Chichester, UK: John Wiley.

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How to Cite close
Sneader, Walter(Apr 2001) History of Sulfonamides. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0003625]