The origins of modern-day cancer chemotherapies can be traced back to their roots in the nineteenth century.
Keywords: anticancer drugs; history; natural products
History of Anticancer Drugs
Graham B Jones, Northeastern University, Boston, Massachusetts, USA
Published online: February 2003
DOI: 10.1038/npg.els.0003630
| Further Reading | |
| Bentley R (1861) Pharm. J. Trans. 1861: 456. | |
| book Brugge J, Curran T and Harlow S (eds) (1991) Origins of Human Cancer: A Comprehensive Review. Plainview, New York: Cold Spring Harbor Laboratory Press. | |
| book Carter S, Glatstein E and Livingston R (eds) (1982) Principles of Cancer Treatment. New York: McGraw-Hill. | |
| book Foyle WO (ed.) (1995) Cancer Chemotherapeutic Agents. Washington DC: ACS. | |
| book Hoare RC (1977) Anthraquinone dyes. US Patent 4,051,155. | |
| book Jones GB (ed.) (1998) Advances in DNA Sequence Specific Agents, vol. 3. Greenwich, CT: JAI Press. | |
| Krumbhaar EB and Krumbhaar HD (1919) The blood and bone marrow in yellow cross gas (mustard gas) poisoning. Changes produced in the bone marrow of fatal cases. Journal of Medical Research 40: 497–507. | |
| Pappenheimer AM and Vance M (1920) Effects of intravenous injections of dichloroethyl sulfide in rabbits, with special reference to its leucotoxic action. Journal of Experimental Medicine 31: 71–95. | |
| Svoboda GH (1961) Alkaloids of Vinca rosea. IX. Extraction and characterization of leurosidine and leurocristine. Lloydia 24: 173–178. | |
| Wall ME, Wani MC, Cook CE et al. (1966) Plant antitumor agents. I. Isolation and structure of camtothecin, a novel alkaloidal leukemia and tumor inhibitor from Camptotheca acuminata. Journal of the American Chemical Society 88: 3888–3890. | |
| Wani MC, Taylor HL, Wall ME, Coggon P and McPhail AT (1971) Plant antitumor agents. VI. Isolation and structure of Taxol, a novel antileukemic and antitumor agent from Taxus brevifolia. Journal of the American Chemical Society 93: 2325–2327. | |
| book Wood HC, Remington JP and Sadtler SP (1899) United States Dispensatory 1067–1070. | |
