B Venkatesh, Institute of Molecular and Cell Biology, Singapore
Published online: September 2005
DOI: 10.1038/npg.els.0005007
Genome sizes of organisms vary widely between and within different phylogenetic groups. Factors contributing to the genome sizes are duplication of a part or the whole of the genome, insertions, spread of repetitive elements and deletion of part or whole chromosomes.
Keywords: genome size; C‐value; chromosome number; minimal genome; synteny
Further Reading
Cavalier‐Smith T (ed.) (1985) The Evolution of Genome Size. New York, NY: Wiley.
Doolittle RF (1997) Microbial genomes opened up. Nature 392: 339–342.
Hinegardner R and Rosen DE (1972) Cellular DNA content and the evolution of teleostean fishes. American Naturalist 106: 621–644.
O'Brien SJ, Menotti‐Raymond M, Murphy WJ, et al. (1999) The promise of comparative genomics in mammals. Science 286: 458–481.
Ohno S (1974) Animal Cytogenetics: Chordata 1. Berlin, Germany: Gebruder Bornträger.
Tiersch TR and Wachtel SS (1991) On the evolution of genome size of birds. Journal of Heredity 82: 363–368.
Venkatesh B, Gilligan P and Brenner S (2000) Fugu: a compact vertebrate reference genome. FEBS Letters 476: 3–7.
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