DNA Markers and Human Evolution

Abstract

Genetic markers reveal nucleotide sequence diversity at different locations and frequencies within the human genome. Since not all loci respond to the same evolutionary forces, one goal of DNA marker use is to understand how information from disparate genomic fragments can generate a realistic understanding of human population changes in space and time.

Keywords: rare alleles; multi‐locus typing; uniparental markers; phylogeny; gene trees

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Further Reading

Cann RL (2001) Genetic clues to dispersal in human populations: retracing the past from the present. Science 291: 1742–1748.

Olson S (2002) Mapping Human History. Boston, USA: Houghton Mifflin Company.

Przeworski M, Hudson RR and Di Renzo A (2000) Adjusting the focus on human variation. Trends in Genetics 16: 296–302.

Tishkoff SA and Williams SM (2002) Genetic analysis of African populations: human evolution and complex disease. Nature Reviews Genetics 3: 611–621.

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How to Cite close
Cann, Rebecca L(Jul 2006) DNA Markers and Human Evolution. In: eLS. John Wiley & Sons Ltd, Chichester. http://www.els.net [doi: 10.1038/npg.els.0005078]