Rebecca L Cann, University of Hawaii‐Manoa, Honolulu, Hawaii, USA
Published online: July 2006
DOI: 10.1038/npg.els.0005078
Genetic markers reveal nucleotide sequence diversity at different locations and frequencies within the human genome. Since not all loci respond to the same evolutionary forces, one goal of DNA marker use is to understand how information from disparate genomic fragments can generate a realistic understanding of human population changes in space and time.
Keywords: rare alleles; multi-locus typing; uniparental markers; phylogeny; gene trees
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| Further Reading | |
| Cann RL (2001) Genetic clues to dispersal in human populations: retracing the past from the present. Science 291: 1742–1748. | |
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| Tishkoff SA and Williams SM (2002) Genetic analysis of African populations: human evolution and complex disease. Nature Reviews Genetics 3: 611–621. | |
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